CAJ | 학술논문

目的探讨早期重度肺挫伤患者血浆(CD62p) 的水平与病情严重程度、预后的相关性.方法 45例重度肺挫伤患者在外伤后2 h、12 h、24 h、3 d、7 d测定血浆CD62p, 并根据预后分为生存组和死亡组.设轻度肺挫伤患者为对照组.结果重度肺挫伤患者的CD62p水平在伤后12 h、24 h、3 d比伤后2 h时有明显的升高(P<0.05).在外伤后的2 h、12 h,生存组与死亡组患者的CD62p水平与对照组比较,差异有统计学意义(P<0.05).而且,死亡组的CD62p水平比生存组明显升高(P<0.05).结论血小板活化程度与重度肺挫伤患者的病情严重程度及其预后相关.
목적 탐토조기중도폐좌상환자혈장(CD62p) 적수평여병정엄중정도、예후적상관성.방법 45례중도폐좌상환자재외상후2 h、12 h、24 h、3 d、7 d측정혈장CD62p, 병근거예후분위생존조화사망조.설경도폐좌상환자위대조조.결과 중도폐좌상환자적CD62p수평재상후12 h、24 h、3 d비상후2 h시유명현적승고(P<0.05).재외상후적2 h、12 h,생존조여사망조환자적CD62p수평여대조조비교,차이유통계학의의(P<0.05).이차,사망조적CD62p수평비생존조명현승고(P<0.05).결론 혈소판활화정도여중도폐좌상환자적병정엄중정도급기예후상관.
Objective To determine the changes of patients with severe pulmonary contusion and the relationship among the serum level of alpha-granular membrane protein (CD62p), the severity of injury and prognosis. Methods The serum level of CD62p, was measured in 45 patients with severe pulmonary contusion on hour 2, hour 12,day 1,3,7 after injured. Forty-five patients were divided into two groups: the survive group and the death group. The levels of CD62p between two groups were compared. Results The serum levels of CD62p in patients with severe pulmonary contusion on 12 hours, 1,3 days after injury were higher than those on 2 hours (P<0.05). The serum levels of CD62p in the survive group and death group on 2 h, 12 hours after injury were higher than those in the control group(P<0.05), and the serum levels of CD62p in the death group were higher than those in the survive group. Conclusion It was helpful in judging the severity of head in jury and prognosis to determine the serum levels of CD62p in patients with severe pulmonary contusion.