中国基层医药
中國基層醫藥
중국기층의약
CHINESE JOURNAL OF PRIMARY MEDICINE AND PHARMACY
2010年
13期
1751-1752
,共2页
肝肿瘤%化学栓塞,治疗性%放射疗法,适形%存活率
肝腫瘤%化學栓塞,治療性%放射療法,適形%存活率
간종류%화학전새,치료성%방사요법,괄형%존활솔
Liver neoplasms%Chemoembolization,therapeutic%Radiotherapy,conformal%Survival rate
目的 探讨肝动脉化疗栓塞(TACE)联合三维适形放射治疗(3D-CRT)治疗不能手术切除的原发性肝癌(PHC)的效果.方法 PHC患者80例,分为TACE治疗(对照组)40例和3D-CRT+TACE治疗(观察组)40例;观察疗效及生存率.结果 观察组有效35例(87.5%),高于对照组的28例(70.0%)(x2=3.89,P＜0.05);观察组1、2、3年的生存率分别为67.5%、55.5%、40.0%,均高于对照组50.0%、27.5%、15.0%(x2=3.4576,x2=3.726,x2=3.635,均P＜0.05);两组不良反应发生率差异无统计学意义(P＞0.05).结论 三维适形放疗联合肝动脉化疗栓塞对不能手术切除的PHC具有较好的疗效,且不良反应可以耐受.
目的 探討肝動脈化療栓塞(TACE)聯閤三維適形放射治療(3D-CRT)治療不能手術切除的原髮性肝癌(PHC)的效果.方法 PHC患者80例,分為TACE治療(對照組)40例和3D-CRT+TACE治療(觀察組)40例;觀察療效及生存率.結果 觀察組有效35例(87.5%),高于對照組的28例(70.0%)(x2=3.89,P＜0.05);觀察組1、2、3年的生存率分彆為67.5%、55.5%、40.0%,均高于對照組50.0%、27.5%、15.0%(x2=3.4576,x2=3.726,x2=3.635,均P＜0.05);兩組不良反應髮生率差異無統計學意義(P＞0.05).結論 三維適形放療聯閤肝動脈化療栓塞對不能手術切除的PHC具有較好的療效,且不良反應可以耐受.
목적 탐토간동맥화료전새(TACE)연합삼유괄형방사치료(3D-CRT)치료불능수술절제적원발성간암(PHC)적효과.방법 PHC환자80례,분위TACE치료(대조조)40례화3D-CRT+TACE치료(관찰조)40례;관찰료효급생존솔.결과 관찰조유효35례(87.5%),고우대조조적28례(70.0%)(x2=3.89,P＜0.05);관찰조1、2、3년적생존솔분별위67.5%、55.5%、40.0%,균고우대조조50.0%、27.5%、15.0%(x2=3.4576,x2=3.726,x2=3.635,균P＜0.05);량조불량반응발생솔차이무통계학의의(P＞0.05).결론 삼유괄형방료연합간동맥화료전새대불능수술절제적PHC구유교호적료효,차불량반응가이내수.
Objective To evaluate the effect of hepatic arterial chemo-embolization( TACE) combined threedimensional conformal radiation therapy (3 D-CRT) in treatment of un- resectable primary hepatocellular cancer (PHC). Methods 80 patients with PHC were divided into TACE therapy(control group) 40 cases and 3D-CRT + TACE treatment( observation group)40 cases,The efficacy and survival rate was observed. Results The rate of effect in observation group were 35 cases (87. 5% ) higher than that 28 cases (70. 0% ) in control group ( x2 = 3. 89, P < 0.05 ) ,The rate of survival in observation group of 1、2、3-year were 67. 5% ,55. 5% ,40. 0% which were higher than that 50. 0% ,27. 5% ,15. 0% in control group( x2 = 3.4576, x2= 3.726, x2 = 3. 635, all P < 0.05), The incidence of adverse reactions in two groups had no significant difference ( P <0.05). Conclusion The three-dimensional conformal radiotherapy combined with transcatheter arterial chemoem-bolization for unresectable primary hepatocellular cancer had a better efficacy,and adverse reactions could be tolerated.
