CAJ | 학술논문

报告1例牛黄解毒片所致重症多形红斑药疹合并急性胰腺炎及上消化道出血并继发巨细胞病毒感染。患者女，20岁。因口、眼、外阴黏膜糜烂、疼痛，伴发热4天，皮肤科检查：全身散在分布黄豆大小水肿性红斑，部分呈靶形，中央水疱或紫癜，眼结膜、口唇、口腔、外阴广泛性充血、糜烂、渗出，被覆白色膜样物质和黄色脓性分泌物。入院诊断重症多形红斑，入院后出现急性胰腺炎、上消化道出血，经及时救治后好转但出现不明原因持续发热，根据血常规、巨细胞病毒血清学结果诊断为巨细胞病毒感染，给予更昔洛韦治疗2周后痊愈。
보고1례우황해독편소치중증다형홍반약진합병급성이선염급상소화도출혈병계발거세포병독감염。환자녀，20세。인구、안、외음점막미란、동통，반발열4천，피부과검사：전신산재분포황두대소수종성홍반，부분정파형，중앙수포혹자전，안결막、구진、구강、외음엄범성충혈、미란、삼출，피복백색막양물질화황색농성분비물。입원진단중증다형홍반，입원후출현급성이선염、상소화도출혈，경급시구치후호전단출현불명원인지속발열，근거혈상규、거세포병독혈청학결과진단위거세포병독감염，급여경석락위치료2주후전유。
A case of bezoar antidotal tablet-induced Stevens-Johnson syndrome complicated by acute pancreatitis and secondary cytomegalovirus infection is reported. A 20-year-old female presented with a 4-day history of painful oral, corneal and vulval erosions and ulcer with fever. Cutaneous examination revealed soybean-sized, edematous erythematous patches scattered over the body, some of these lesions were targetshaped with or without central vesicles and purpura. There were generalized hyperemia and erosions covered by white membranous material and yellow purulent secretions. After hospitalized with a diagnosis of StevensJohnson syndrome, she developed acute pancreatitis and upper gastrointestinal tract bleeding. Her condition improved markedly after timely management, but fever appeared subsequently. The results of blood routine test and serological tests for cytomegalovirus were suggestive of cytomegalovirus infection. The patient completely recovered after 2-week treatment with ganciclovir.