CAJ | 학술논문

目的探讨腔内近距离放疗配合体外放疗和同步化疗治疗中央型肺癌的疗效.方法 42例中央型肺癌患者随机分为治疗组和对照组.采用腔内近距离放疗配合体外放疗和同步化疗治疗累及气管、支气管的中央型肺癌21例.结果治疗组和对照组总有效率分别为85.7%和57.1%,差异有统计学意义(P＜0.05).主要不良反应为刺激性剧烈咳嗽和骨髓抑制.结论腔内近距离放疗中央型肺癌能迅速改善由气道阻塞引起的临床症状,与体外放疗和同步化疗联合应用能达到较好的治疗效果.
목적 탐토강내근거리방료배합체외방료화동보화료치료중앙형폐암적료효.방법 42례중앙형폐암환자수궤분위치료조화대조조.채용강내근거리방료배합체외방료화동보화료치료루급기관、지기관적중앙형폐암21례.결과 치료조화대조조총유효솔분별위85.7%화57.1%,차이유통계학의의(P＜0.05).주요불량반응위자격성극렬해수화골수억제.결론 강내근거리방료중앙형폐암능신속개선유기도조새인기적림상증상,여체외방료화동보화료연합응용능체도교호적치료효과.
Objective To evaluate the acute side effects and efficacy of the intraluminal brachytherapy combined with external radiation and synchronous chemotherapy in the treatment of bronchial lung cancer.Methods From June 2001 to June 2003,42 patients with bronchial lung cancer were divided into treatment group and control group randomly.21 lung cancer patients with major airway obstruction were treated by combined intralumihal brachytherapy with external beam radiotherapy and synchronous chemotherapy.Results The overall response rate(CR+PR)in treatment group and control group were 85.7% and 57.1%(P＜0.05).There were no serious complication during the treatment except for irritant cough and leukocytopenia.Conclusion Intraluminal brachytherapy may result in symptom improvement in patients with major airway occlusion of lung cancer.The intraluminal bmchytherapy combined with external beam radiothempy and synchronous chemotherapy is an effective method in treatment of lung cancer.