CAJ | 학술논문

目的:观察穴位敷贴对缓解期哮喘患者血清中嗜酸粒细胞阳离子蛋白(ECP)、6-酮-前列腺素F1α(6-Keto-PGF1 α)和血栓素B2(TXB2)的影响.方法:门诊临床缓解期哮喘患者300例,分为治疗组(150例)和对照组(150例),对照组给予基础治疗,治疗组除进行与对照组相同的基础治疗外,于每年7月、12月进行穴位敷贴治疗,连续治疗2年为1个疗程.两组患者每年复查ECP、6-Keto-PGF1 α和TXB2,填写"哮喘控制测试表",进行比较分析.结果:经过穴位敷贴后患者发作次数、呼吸困难情况、药物使用频次均较对照组有减少,反映气道炎症的ECP和气道状态的6-Keto-PGF1α、TXB2水平均有明显改善(P＜0.05).结论:中药穴位敷贴防治哮喘复发确有疗效,对哮喘患者改善症状,以及ECP、6-Keto-PGF1α和TXB2均有显著良性影响.
목적:관찰혈위부첩대완해기효천환자혈청중기산립세포양리자단백(ECP)、6-동-전렬선소F1α(6-Keto-PGF1 α)화혈전소B2(TXB2)적영향.방법:문진림상완해기효천환자300례,분위치료조(150례)화대조조(150례),대조조급여기출치료,치료조제진행여대조조상동적기출치료외,우매년7월、12월진행혈위부첩치료,련속치료2년위1개료정.량조환자매년복사ECP、6-Keto-PGF1 α화TXB2,전사"효천공제측시표",진행비교분석.결과:경과혈위부첩후환자발작차수、호흡곤난정황、약물사용빈차균교대조조유감소,반영기도염증적ECP화기도상태적6-Keto-PGF1α、TXB2수평균유명현개선(P＜0.05).결론:중약혈위부첩방치효천복발학유료효,대효천환자개선증상,이급ECP、6-Keto-PGF1α화TXB2균유현저량성영향.
Objective: To observe the influence of acupoint application therapy on serum eosinophilic granulocyte cationic protein (ECP), 6 keto prostaglandin F 1 (6-keto-PGF 1) and thromboxane B2 (TXB2). Methods: 300 cases of asthma out-patients in a remission period were divided into a treatment group (150 cases) and a control group (150 cases). The control group was given the basic treatment, and the treatment group was given external application on the acupoints in July and December every year, as well as the basic treatment of the control group, with continuous treatment for 2 years as one course. ECP, 6-keto-PGF 1, and TXB2 were checked every year in the patients of the two groups, and an Asthma Control Test Table was filled in for comparative analysis. Results: After the external application on the acupoints, the frequency of seizures, dyspnea and frequency of medication administration of the patients had been more reduced than those in the control group, indicating that the levels of ECP in inflammation of air passage and of 6-eto-GF 1 and TXB2 were obviously improved (P＜0.05). Conclusion: The herbal application on the acupoints is effective and positively influential to the improvement of the symptoms in the asthma patients and to ECP, 6-keto-PGF 1, and TXB2 remarkably.