中华糖尿病杂志
中華糖尿病雜誌
중화당뇨병잡지
CHINESE JOURNAL OF DIABETES
2000年
5期
269-271
,共3页
糖尿病周围神经病变%蛋白非酶糖基化%醛糖还原酶抑制剂
糖尿病週圍神經病變%蛋白非酶糖基化%醛糖還原酶抑製劑
당뇨병주위신경병변%단백비매당기화%철당환원매억제제
Diabetic peripheral neuropathy (DPN) Protein nonenzymatic glycation Aldose reductase inhibitor
目的观察葛根素注射液治疗糖尿病周围神经病变(DPN)的疗效.方法采用葛根素注射液治疗DPN 66例,同时与甲钴胺治疗的22例作对照,观察葛根素注射液对DPN患者肌电图、空腹血糖、糖化血红蛋白、血液流变学及红细胞山梨醇的影响.结果治疗组显效率为51.51%,对照组为22.72%(P＜0.01).治疗组总有效率为89.39%,对照组为58.10%(P＜0.05),治疗组在治疗后,空腹血糖略有下降(P＞0.05),糖化血红蛋白有显著下降(P＜0.01),血流变学有明显改善.红细胞山梨醇有明显下降(P＜0.01).结论葛根素治疗DPN有较好疗效.
目的觀察葛根素註射液治療糖尿病週圍神經病變(DPN)的療效.方法採用葛根素註射液治療DPN 66例,同時與甲鈷胺治療的22例作對照,觀察葛根素註射液對DPN患者肌電圖、空腹血糖、糖化血紅蛋白、血液流變學及紅細胞山梨醇的影響.結果治療組顯效率為51.51%,對照組為22.72%(P＜0.01).治療組總有效率為89.39%,對照組為58.10%(P＜0.05),治療組在治療後,空腹血糖略有下降(P＞0.05),糖化血紅蛋白有顯著下降(P＜0.01),血流變學有明顯改善.紅細胞山梨醇有明顯下降(P＜0.01).結論葛根素治療DPN有較好療效.
목적관찰갈근소주사액치료당뇨병주위신경병변(DPN)적료효.방법채용갈근소주사액치료DPN 66례,동시여갑고알치료적22례작대조,관찰갈근소주사액대DPN환자기전도、공복혈당、당화혈홍단백、혈액류변학급홍세포산리순적영향.결과치료조현효솔위51.51%,대조조위22.72%(P＜0.01).치료조총유효솔위89.39%,대조조위58.10%(P＜0.05),치료조재치료후,공복혈당략유하강(P＞0.05),당화혈홍단백유현저하강(P＜0.01),혈류변학유명현개선.홍세포산리순유명현하강(P＜0.01).결론갈근소치료DPN유교호료효.
Objective To investigate the effects of puerar in injection on the diabetic preipheral neuropathy (DPN).Methods Comparing sixty-six cases in puerar treat group with twenty-two cases in mecobalamin control group.And observing the effects of puerar in injection on the electromyo graphy,FBG,HbAlc,hemorheology and erythrocyte polyol.Results Marked effective rate:51.51% (treat group);22.72% (control group) ( P <0 01).Effective rate:89.39% (treat group ); 58.10% (control group) ( P <0 05).In treat group after treatment,FBG fell slightly without any meaning in statistics ( P >0 05);HbA1c decreased markedly ( P <0 01);hemorheology improved evidently;erythrocyte polyol decreased conspicuously ( P <0 01).Conclusion Puerar in injection has a good effect in DPN remedy.
