中华劳动卫生职业病杂志
中華勞動衛生職業病雜誌
중화노동위생직업병잡지
CHINESE JOURNAL OF INDUSTRIAL HYGIENE AND OCCUPATIONAL DISEASES
2012年
4期
265-267
,共3页
毕莹%毛翎%王炳森%施瑾%周韶炜%陈子丹%卞陆琴%张悦
畢瑩%毛翎%王炳森%施瑾%週韶煒%陳子丹%卞陸琴%張悅
필형%모령%왕병삼%시근%주소위%진자단%변륙금%장열
粉尘%支气管检查%病理学
粉塵%支氣管檢查%病理學
분진%지기관검사%병이학
Dust%Occupational exposure%Bronchoscopy%Pathology
目的 探讨经纤维支气管镜肺活检肺组织标本病理学改变在尘肺诊断中的价值.方法 2011年5月至2011年9月在我院经支气管肺活检(TBLB)取得肺组织标本的职业性粉尘接触者35例,同期经胸腔镜或开胸肺叶切除取得的肺组织标本的无粉尘接触史的患者27例,进行肺组织纤维组织增生、类结节、粉尘沉积和晶粒偏光等病理指标对比.结果 接尘组中度粉尘沉着6例(17.1%),与对照组(0)相比,差异有统计学意义(P<0.05).接尘组肺组织纤维化增生28例(80.0%),明显高于对照组(11例,40.7%),差异有统计学意义(P<0.05).接尘组有6例发现晶粒偏光阳性,6例发现类结节,对照组病例无晶粒偏光阳性或类结节改变.结论 TBLB病理检查能取得接触粉尘引起肺内相关改变的依据,在尘肺病的诊断中有一定的应用价值.
目的 探討經纖維支氣管鏡肺活檢肺組織標本病理學改變在塵肺診斷中的價值.方法 2011年5月至2011年9月在我院經支氣管肺活檢(TBLB)取得肺組織標本的職業性粉塵接觸者35例,同期經胸腔鏡或開胸肺葉切除取得的肺組織標本的無粉塵接觸史的患者27例,進行肺組織纖維組織增生、類結節、粉塵沉積和晶粒偏光等病理指標對比.結果 接塵組中度粉塵沉著6例(17.1%),與對照組(0)相比,差異有統計學意義(P<0.05).接塵組肺組織纖維化增生28例(80.0%),明顯高于對照組(11例,40.7%),差異有統計學意義(P<0.05).接塵組有6例髮現晶粒偏光暘性,6例髮現類結節,對照組病例無晶粒偏光暘性或類結節改變.結論 TBLB病理檢查能取得接觸粉塵引起肺內相關改變的依據,在塵肺病的診斷中有一定的應用價值.
목적 탐토경섬유지기관경폐활검폐조직표본병이학개변재진폐진단중적개치.방법 2011년5월지2011년9월재아원경지기관폐활검(TBLB)취득폐조직표본적직업성분진접촉자35례,동기경흉강경혹개흉폐협절제취득적폐조직표본적무분진접촉사적환자27례,진행폐조직섬유조직증생、류결절、분진침적화정립편광등병리지표대비.결과 접진조중도분진침착6례(17.1%),여대조조(0)상비,차이유통계학의의(P<0.05).접진조폐조직섬유화증생28례(80.0%),명현고우대조조(11례,40.7%),차이유통계학의의(P<0.05).접진조유6례발현정립편광양성,6례발현류결절,대조조병례무정립편광양성혹류결절개변.결론 TBLB병리검사능취득접촉분진인기폐내상관개변적의거,재진폐병적진단중유일정적응용개치.
Objective To explore the role of transbronchial lung biopsy (TBLB) in pathologic diagnosis of pneumoconiosis.Methods In our hospital during May 2011 and Sep 2011,the TBLB samples from 35 cases occupationally exposed to dusts were compared with the video-assisted thoracoscopic surgery or lobectomy samples from 27 cases not exposed to dusts for pathological indexes,including fibrotic proliferation,nodule or nodule-like,dust deposition and needle-shaped birefringent particles.Results In group exposed to dusts,there were 6 cases (17.1%) with the moderate dust deposition and 28 cases (80.0%) with fibrotic proliferation.But in group not exposed to dusts,there were 0 case with the moderate dust deposition and 11 cases (40.0%) with fibrotic proliferation.There were significant differences between two groups (P<0.05).In group exposed to dusts,there were 6 cases (17.1%) with Nodules-like and needle-shaped birefringent particles,but in group not exposed to dusts,there was 0 case with Nodules-like and needle-shaped birefringent particles.Conclusion TBLB could provide the evidence of pathological changes in lung tissue induced by dusts,and TBLB play an important role in pneumoconiosis diagnosis.