CAJ | 학술논문

目的探索螺旋CT双期扫描与CA19-9检测相结合在胰腺癌术前可切除性评价中的应用价值. 方法回顾分析2002年2月至2006年2月本院52例胰腺癌患者的临床资料,根据螺旋CT双期扫描结果和血清CA19-9检测结果进行胰腺癌术前可切除性评价. 结果 CT判断胰腺癌不可切除的准确率为100%,而判断可切除的准确率为73.30%.随着胰腺癌浸润程度的进展,CA19-9水平有增高的趋势.局部侵犯组CA19-9均值与可切除组和转移组CA19-9均值差异无统计学意义.以CA19-9大于150 U/ml作为不可切除判断的临界值,在不可切除组41例患者中,只有10例患者的血清CA19-9水平大于150 U/ml,占24.39%. 结论血清CA19-9水平随胰腺癌浸润进展程度有逐渐升高的趋势,但CA19-9水平并不能反应胰周大血管受侵犯.CA19-9检测与CT结合在胰腺癌术前可切除性评价中的临床实用价值有限.
목적 탐색라선CT쌍기소묘여CA19-9검측상결합재이선암술전가절제성평개중적응용개치. 방법 회고분석2002년2월지2006년2월본원52례이선암환자적림상자료,근거라선CT쌍기소묘결과화혈청CA19-9검측결과진행이선암술전가절제성평개. 결과 CT판단이선암불가절제적준학솔위100%,이판단가절제적준학솔위73.30%.수착이선암침윤정도적진전,CA19-9수평유증고적추세.국부침범조CA19-9균치여가절제조화전이조CA19-9균치차이무통계학의의.이CA19-9대우150 U/ml작위불가절제판단적림계치,재불가절제조41례환자중,지유10례환자적혈청CA19-9수평대우150 U/ml,점24.39%. 결론 혈청CA19-9수평수이선암침윤진전정도유축점승고적추세,단CA19-9수평병불능반응이주대혈관수침범.CA19-9검측여CT결합재이선암술전가절제성평개중적림상실용개치유한.
Objective To investigate the value of spiral computed tomography (CT) combined with CA19-9 in predicting the resectability of patients with pancreatic carcinoma. Method Preoperative clinical features and serum CA19-9 levels of 52 patients with pancreatic cancer between February 2002 and February 2006 were reviewed. Preoperatively respectability was evaluated retrospectively from a complete history and CT imaging. Patients were divided as resectable group (A), unresectable with invasion into large vessels group(B), unresectable with metastasis group ( C ). Results For prediction of unresectabiliy, spiral CT had accuracy of 100% ,and for prediction of resectability , the accuracy was 73.30%. The level of serum CA19-9 increased along with advancing of tumor, and serum CA19-9 between group A and group C was significanlly different ( P<0.05 ), but no differences between group B and group A, group B and group C (P>0.05). If using CA19-9 level of 150 U/ml as a threshold to determine unresectability, among 41 patients of group B and C,only 10 (24.39%) patients had CA19-9 level higher than 150 U/ml. On the other hand,patients of group A had serum CA19-9 level lower than 150 U/ml. Conclusion The level of serum CA19-9 increases along with advancing of tumor, but the level of serum CA19-9 can not reflect tumor local invasion. Application of spiral CT combined with CA19-9 in predicting resectability for the pancreatic carcinoma is limited.