CAJ | 학술논문

目的观察艾迪注射液和槐耳颗粒配合介入疗法治疗原发性肝癌的临床疗效及毒副作用.方法将43例原发性肝癌患者随机分为两组,即治疗组22例(艾迪注射液和槐耳颗粒联合肝癌介入治疗)与对照组21例(单纯肝癌介入治疗),对两组患者近期疗效、毒副作用进行比较.结果治疗组有效率59.1%,对照组为33.3%,差异有统计学意义(P＜0.01);治疗组临床获益率(86.4%)高于对照组(71.4%),差异也有统计学意义21例(P＜0.05);治疗组患者生活质量明显提高,T细胞及NK细胞活性均有提高,且均优于对照组(均P＜0.05);治疗组胃肠反应发生率和白细胞下降率均较对照组低(均P＜0.05).结论艾迪注射液和槐耳颗粒配合介入疗法治疗原发性肝癌能提高近期疗效,改善患者免疫活性,提高生活质量,且不良反应小.
목적 관찰애적주사액화괴이과립배합개입요법치료원발성간암적림상료효급독부작용.방법 장43례원발성간암환자수궤분위량조,즉치료조22례(애적주사액화괴이과립연합간암개입치료)여대조조21례(단순간암개입치료),대량조환자근기료효、독부작용진행비교.결과 치료조유효솔59.1%,대조조위33.3%,차이유통계학의의(P＜0.01);치료조림상획익솔(86.4%)고우대조조(71.4%),차이야유통계학의의21례(P＜0.05);치료조환자생활질량명현제고,T세포급NK세포활성균유제고,차균우우대조조(균P＜0.05);치료조위장반응발생솔화백세포하강솔균교대조조저(균P＜0.05).결론 애적주사액화괴이과립배합개입요법치료원발성간암능제고근기료효,개선환자면역활성,제고생활질량,차불량반응소.
Objective To observe the clinical effiect and toxicity of Aidi injection and Huaier particles combined with interventional therapy for primary liver cancer patients.Methods 43 paients with primary liver cancer were randomly divided into two groups:the treatment group 22 cases(Aidi injection and Huaier particles combined with interventional therapy to the primary liver cancer)and the control group 21 cases(treated only with intervention therapy of liver cancer).The recent efficiency and toxicity of the two groups were compared.Results The effective rate of the treatment group was 59.1%,and in control group was 33.3%,and the differences was significant(P＜0.01).In the treatment group,clinical benefit rate was 86.4%higher than than of the control group(71.4%),and the difference was significant(P＜0.05);The treatment group significantly improved the quality of life of patients,T cell and NK cell activity were improved,and better than the control group(P＜0.05).The incidence of gastrointestinal reactions and neutropenia rate in treatment group was lower than the control group(all P＜0.05).Conclusion Aidi injection and Huaier Granule interventional therapy could improve the curative effect of primary liver cancer、the immune activity、quality of patients life,and the adverse effects.