CAJ | 학술논문

近年来全基因组关联研究在世界范围内发展迅猛.发作性睡病是一种慢性非进行性睡眠障碍,常在青少年期起病并持续终生,对患者身心健康影响很大.本文对近年来世界范围内针对发作性睡病的全基因组关联研究、所面临的挑战以及对未来研究的发展趋势进行分析阐述,为进一步探究发作性睡病的遗传机制提供指导.
근년래전기인조관련연구재세계범위내발전신맹.발작성수병시일충만성비진행성수면장애,상재청소년기기병병지속종생,대환자신심건강영향흔대.본문대근년래세계범위내침대발작성수병적전기인조관련연구、소면림적도전이급대미래연구적발전추세진행분석천술,위진일보탐구발작성수병적유전궤제제공지도.
Genome-wide association study(GWAS) has being developed rapidly in recent years worldwide. Narcolepsy is a chronic non-progressive sleep disorder, which often begin in the adolescent and last for a lifetime, making patients great impact both on physical and mental. The present paper reviewed the important progresses worldwide attained in GWAS of narcolepsy in recent years. Then it is also expounded the challenges we are facing nowadays in GWAS as well as the future study direction. The information outlined in this paper provides us a valuable guidance upon further exploration into genetic mechanism of narcolepsy.