中华内分泌代谢杂志
中華內分泌代謝雜誌
중화내분비대사잡지
CHINESE JOURNAL OF ENDOCRINOLOGY AND METABOLISM
2009年
2期
174-176
,共3页
沈兴平%邹森彪%吴豪杰%张岩
瀋興平%鄒森彪%吳豪傑%張巖
침흥평%추삼표%오호걸%장암
糖尿病,2型%晚期糖基化终末产物受体%氧化应激
糖尿病,2型%晚期糖基化終末產物受體%氧化應激
당뇨병,2형%만기당기화종말산물수체%양화응격
Diabetes mellitus,type 2%Advanced glycation end product receptor%Oxidative stress
探讨2型糖尿病高血压患者血浆内源性分泌型晚期糖基化终末产物受体(esRAGE)与氧化应激的关系.结果 显示2型糖尿病患者esRAGE与体重指数(BMI,r=-0.33)、舒张压(r=-0.38)、氧化应激均显著相关(均P<O.05).提示2型糖尿病高血压患者血浆esRAGE水平下降,且与BMI、舒张压和氧化应激有关.
探討2型糖尿病高血壓患者血漿內源性分泌型晚期糖基化終末產物受體(esRAGE)與氧化應激的關繫.結果 顯示2型糖尿病患者esRAGE與體重指數(BMI,r=-0.33)、舒張壓(r=-0.38)、氧化應激均顯著相關(均P<O.05).提示2型糖尿病高血壓患者血漿esRAGE水平下降,且與BMI、舒張壓和氧化應激有關.
탐토2형당뇨병고혈압환자혈장내원성분비형만기당기화종말산물수체(esRAGE)여양화응격적관계.결과 현시2형당뇨병환자esRAGE여체중지수(BMI,r=-0.33)、서장압(r=-0.38)、양화응격균현저상관(균P<O.05).제시2형당뇨병고혈압환자혈장esRAGE수평하강,차여BMI、서장압화양화응격유관.
The relationship between plasma level of endogenous secretory receptor of advanced glyeation end products(esRAGE)and oxidative stress in diabetic patients with hypertension was investigated.The results showed that there was significant negative correlation between esRAGE and body mass index(BMI,r=-0.33), diastolic blood pressure(DBP,r=-O.38)and oxidative stress(all P<0.05).The levels of plasma esRAGE decreased significantly in diabetic patients with hypertension.BMI,DBP and oxidative stress may participate in determinining the esRAGE level in diabetic patients complicated with hypertension.
