CAJ | 학술논문

目的探讨发型溃疡性结肠炎致中毒性巨结肠的临床表现及诊治方法.方法回顾性分析2003年6月至2008年10月收治的5例初发型UC致中毒性巨结肠患者的临床资料.结果 5例患者首发症状均为腹痛、腹胀,因口服泻剂而诱发中毒性巨结肠,2例发生肠穿孔.4例女性患者出现神志异常,4例行磁共振检查,3例示腔隙性脑梗塞.该5例患者均接受手术探查,且在术前均未确立溃疡性结肠炎的诊断.5例均行部分结肠切除及肠造口术,平均手术2.4次.术后死亡1例.吻合口瘘1例,吻合口狭窄1例.结论腹痛、腹胀及服用导泻剂后临床症状加重是初发型溃疡性结肠炎致中毒性巨结肠常见的临床表现.
목적 탐토발형궤양성결장염치중독성거결장적림상표현급진치방법.방법 회고성분석2003년6월지2008년10월수치적5례초발형UC치중독성거결장환자적림상자료.결과 5례환자수발증상균위복통、복창,인구복사제이유발중독성거결장,2례발생장천공.4례녀성환자출현신지이상,4례행자공진검사,3례시강극성뇌경새.해5례환자균접수수술탐사,차재술전균미학립궤양성결장염적진단.5례균행부분결장절제급장조구술,평균수술2.4차.술후사망1례.문합구루1례,문합구협착1례.결론 복통、복창급복용도사제후림상증상가중시초발형궤양성결장염치중독성거결장상견적림상표현.
Objective To analyze the clinical manifestations and treatment for toxic megacolon induced by drastic cathartics inpatients with an unknown history of ulcerative colitis. Methods The clinical data of 5 patients with toxic megacolon induced by ulcerative colitis with initial onset type from June 2003 to October 2008 were analyzed retrospectively. Results In 5 cases, the first symptom was abdominal pain and distention. After taking cathartics, these 5 cases were complicated with toxic megaeolon and 2 cases suffering from intestinal perforation. Four female patients suffered from transient unconsciousness, in which 3 patients were found with cerebral lacunal infarction identified by magnetic field diffusion-weighted imaging. All 5 cases underwent exploration, colectomy and ostomy, one patient died perioperatively, anastomotic fistula and anastomotic constriction developed in one each cases. Conclusions The most common clinical manifestations of toxic megacolon induced by ulcerative colitis are abdominaigia, abdominal distention. Emergency therapeutic strategy consists of partial culectomy and ostomy.