中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2010年
7期
12-14
,共3页
梅毒螺旋体%神经梅毒%脑脊液%公共卫生
梅毒螺鏇體%神經梅毒%腦脊液%公共衛生
매독라선체%신경매독%뇌척액%공공위생
Treponema pallidum%NeurosyphilisCerebrospinal fluid%Public health
目的 探讨神经梅毒患者的临床表现、实验室检查、影像学特征、诊断、治疗及预后.方法 对我院2000年至2009年诊治的37例神经梅毒患者的临床资料进行回顾性分析.结果 本组37例患者中,脑血管型神经梅毒16例,麻痹性痴呆13例,脊髓梅毒3例,脑膜型神经梅毒2例,无症状神经梅毒2例,树胶肿型神经梅毒1例.血清快速血浆反应素(RPR)试验、梅毒螺旋体血凝试验(TPHA)试验均阳性.脑脊液(CSF)的RPR试验阳性率为67.6%,TPHA试验阳性率为100%;脑脊液检查蛋白增高阳性率为64.9%,细胞数增高阳性率为54.1%.结论 神经梅毒患者的临床表现复杂,诊断应结合临床表现、实验室及影像学检查综合分析,脑脊液检查是关键,应争取早期诊断、早期治疗以改善预后.同时应从公共卫生的的理念上去规划和实施梅毒的预防和治疗,以降低神经梅毒的发病率.
目的 探討神經梅毒患者的臨床錶現、實驗室檢查、影像學特徵、診斷、治療及預後.方法 對我院2000年至2009年診治的37例神經梅毒患者的臨床資料進行迴顧性分析.結果 本組37例患者中,腦血管型神經梅毒16例,痳痺性癡呆13例,脊髓梅毒3例,腦膜型神經梅毒2例,無癥狀神經梅毒2例,樹膠腫型神經梅毒1例.血清快速血漿反應素(RPR)試驗、梅毒螺鏇體血凝試驗(TPHA)試驗均暘性.腦脊液(CSF)的RPR試驗暘性率為67.6%,TPHA試驗暘性率為100%;腦脊液檢查蛋白增高暘性率為64.9%,細胞數增高暘性率為54.1%.結論 神經梅毒患者的臨床錶現複雜,診斷應結閤臨床錶現、實驗室及影像學檢查綜閤分析,腦脊液檢查是關鍵,應爭取早期診斷、早期治療以改善預後.同時應從公共衛生的的理唸上去規劃和實施梅毒的預防和治療,以降低神經梅毒的髮病率.
목적 탐토신경매독환자적림상표현、실험실검사、영상학특정、진단、치료급예후.방법 대아원2000년지2009년진치적37례신경매독환자적림상자료진행회고성분석.결과 본조37례환자중,뇌혈관형신경매독16례,마비성치태13례,척수매독3례,뇌막형신경매독2례,무증상신경매독2례,수효종형신경매독1례.혈청쾌속혈장반응소(RPR)시험、매독라선체혈응시험(TPHA)시험균양성.뇌척액(CSF)적RPR시험양성솔위67.6%,TPHA시험양성솔위100%;뇌척액검사단백증고양성솔위64.9%,세포수증고양성솔위54.1%.결론 신경매독환자적림상표현복잡,진단응결합림상표현、실험실급영상학검사종합분석,뇌척액검사시관건,응쟁취조기진단、조기치료이개선예후.동시응종공공위생적적이념상거규화화실시매독적예방화치료,이강저신경매독적발병솔.
Objective To investigate the clinical manifestations, laboratory tests, imaging features,diagnosis, treatment and prognosis of neurosyphilis.Methods The 37 cases of patients with neurosyphilis admitted in our hospital from 2000 to 2009 were analyzed retrospectively.Results Among the 37cases, the cerebral vascular neurosyphilis in 16 cases, paralytic dementia in 13 cases, spinal cord syphilis in 3 cases, meningeal neural syphilis in 2 cases, asymptomatic neurosyphilis in 2 cases, gumma type in 1case.Serum rapid plasma reagin(RPR)test and treponema pallidum hemagglutination assay(TPHA)test were all positive.the positive rate of cerebrospinal fluid(CSF)the RPR was 67.6%, the TPHA was 100% ,the cerebrospinal fluid examination revealed CSF protein increase was 64.9% and cell number elevation was 54.1%.Conclusions Because of theclinical manifestations of neurosyphilis are complex, the diagnosis should be comprehensive analysis, according to the clinical characteristics, laboratory and imaging features,the cerebrospinal fluid examination is the key.It is should be strived for early diagnosis and treatment to improve prognosis.At the same time, in order to reduce the incidence of neurosyphilis, there should go up to plan and enforce the prevention and treatment of syphilis from the concept of public health.
