CAJ | 학술논문

目的评价肾动态显像和Cockcroft-Gault公式法在肾功能不同分期时估测肾小球滤过率的价值.方法选择非透析的慢性肾脏疾病(CKD)患者41例,将患者分为两组:分别为GFR＜60 ml/(min.1.73 m2)(24例),GFR＞60 ml/(min.1.73 m2)(17例).以双血浆法测得的肾小球滤过率为金标准,将肾动态显像法所测值分别于双血浆法测得的值进行相关分析.结果肾动态显像法与双血浆法有很好的相关性,相关系数分别为0.953(P＜0.01).肾动态显像法所测肾小球滤过率(单位:ml/(min.1.73 m2)分别为,1组(20.62±10.54)、2组(65.86±20.05),肾动态显像法所测肾小球滤过率分别与双血浆法相比均有显著性差异,较低的估计了真实值.结论肾动态显像法与双血浆法测得GFR有较好相关性,肾动态显像不同程度的低估了肾小球滤过率.
목적 평개신동태현상화Cockcroft-Gault공식법재신공능불동분기시고측신소구려과솔적개치.방법 선택비투석적만성신장질병(CKD)환자41례,장환자분위량조:분별위GFR＜60 ml/(min.1.73 m2)(24례),GFR＞60 ml/(min.1.73 m2)(17례).이쌍혈장법측득적신소구려과솔위금표준,장신동태현상법소측치분별우쌍혈장법측득적치진행상관분석.결과 신동태현상법여쌍혈장법유흔호적상관성,상관계수분별위0.953(P＜0.01).신동태현상법소측신소구려과솔(단위:ml/(min.1.73 m2)분별위,1조(20.62±10.54)、2조(65.86±20.05),신동태현상법소측신소구려과솔분별여쌍혈장법상비균유현저성차이,교저적고계료진실치.결론 신동태현상법여쌍혈장법측득GFR유교호상관성,신동태현상불동정도적저고료신소구려과솔.
Objective To investigate the value of dynamic imaging on estimating GFR in patients with chronic kidney disease of different stages.Methods Forty-one patients with chronic kidney disease were included. The patients were taken into stage 1 when the GFR was below than 60 ml/(min·1.73 m2) ,and stage 2when the GFR was more than 60 ml/( min·1.73 m2 ) Taking the GFR measured by the duple plasma as the standard, the correlations of GFR measured by renal dynamic imaging and the Cockcroft-Gault formula were analyzed using Pearson correlations analysis. Results The correlation coefficients for dynamic imaging was 0.953(P＜ 0.01 ). The GFR( ml/( min·1.73 m2) obtained by dynamic imaging method and two-sample method was displayed as follows: stage 1 ( 20.62 ± 10.54 ) and ( 26.28 ± 13.1 ); stage2 ( 65.86 ± 20.05 ) and ( 84.70 ±16.89). There was significant difference when dynamic imaging method compared with the two-sample method.Conclusion The dynamic imaging method had a good correlation with the dual plasma sampling method in different stages. There were significant differences when dynamic imaging method compared with GFR-dual plasma sampling method in the full set and in all different stages.