CAJ | 학술논문

介绍了诱导拆分法合成D（-）-酒石酸的合成工艺、操作过程和控制条件,发现拆分的最优条件为：在28℃放晶种,缓慢冷却到有晶体开始析出1分钟后立即过滤,即可将外消旋酒石酸铵钠拆分成左旋酒石酸铵钠和右旋酒石酸铵钠,再利用置换反应就能得到D（-）-酒石酸。旋光度为[α]2D0-12.19°（c=20,H2O）,拆分率大有提高,为46.5%。
개소료유도탁분법합성D（-）-주석산적합성공예、조작과정화공제조건,발현탁분적최우조건위：재28℃방정충,완만냉각도유정체개시석출1분종후립즉과려,즉가장외소선주석산안납탁분성좌선주석산안납화우선주석산안납,재이용치환반응취능득도D（-）-주석산。선광도위[α]2D0-12.19°（c=20,H2O）,탁분솔대유제고,위46.5%。
The synthesis method,operation process and control condition of induction split D（-）-tartaric acid with induction split were introduced,and found that the optimal conditions for resolution were that in the 28 ℃ put the seed,slow cooling to have crystal,and 1 min separation immediately after the filter,and the filter can spin tartaric acid and ammonium away sodium left spin tartaric acid sodium ammonium and a right-handed,using ammonium tartaric acid sodium placement response can get D（-）-tartaric acid.The optical rotations was [α]20D=-12.19 °（c=20,H2O）,and the resolution ratio was greatly enhanced for 46.5%.