广州化工
廣州化工
엄주화공
GUANGZHOU CHEMICAL INDUSTRY AND TECHNOLOGY
2011年
17期
32-34
,共3页
陈贯虹%孔学%高永超%王加宁%迟建国%邱维忠
陳貫虹%孔學%高永超%王加寧%遲建國%邱維忠
진관홍%공학%고영초%왕가저%지건국%구유충
间苯三酚%合成%酰化%生物活性
間苯三酚%閤成%酰化%生物活性
간분삼분%합성%선화%생물활성
phloroglucinol%acetylation%synthesis%biological activity
以2,4-二乙酰基间苯三酚为基础,通过改变一个酰基碳链的长度,合成了三个间苯三酚乙酰基衍生物,目标化合物经LC-MS进行了确证,室内生测试验结果表明,2-乙酰基-4-丙酰基间苯三酚与2-乙酰基-4-丁酰基间苯三酚对立枯丝核菌、禾谷丝核菌、灰葡萄孢具有明显的抑制作用。
以2,4-二乙酰基間苯三酚為基礎,通過改變一箇酰基碳鏈的長度,閤成瞭三箇間苯三酚乙酰基衍生物,目標化閤物經LC-MS進行瞭確證,室內生測試驗結果錶明,2-乙酰基-4-丙酰基間苯三酚與2-乙酰基-4-丁酰基間苯三酚對立枯絲覈菌、禾穀絲覈菌、灰葡萄孢具有明顯的抑製作用。
이2,4-이을선기간분삼분위기출,통과개변일개선기탄련적장도,합성료삼개간분삼분을선기연생물,목표화합물경LC-MS진행료학증,실내생측시험결과표명,2-을선기-4-병선기간분삼분여2-을선기-4-정선기간분삼분대립고사핵균、화곡사핵균、회포도포구유명현적억제작용。
Three phloroglucinol acetylated derivatives were synthesized with 2,4-diacetylphloroglucinol as the basis structure.All the compounds synthesized were confirmed by LC-MS.The results of preliminary bioassay showed that two compounds of 2-acetyl-4-propionylphloroglucinol and 2-acetyl-4-butyrylphloroglucinol had obvious inhibitive effect on Rhizoctonia solani,Rhizoctonia cerealis,and Botrytis cinerea.
