CAJ | 학술논문

目的探讨糖尿病微血管病变患者的QT离散度(QTd)变化及其意义。方法分析50例糖尿病并发肾病和[或]视网膜病变患者的体表12导联同步心电图，与52例单纯糖尿病患者及50例正常人作对照。结果糖尿病肾病和[或]视网膜病变组的QTd显著高于其余两组(P＜0.01)。结论①糖尿病微血管病变可能导致心肌细胞损害影响心室复极，从而使QTd增大。②糖尿病患者QTd增大时，可提示微血管病变的发生，即QTd可作为糖尿病微血管病变的一项参考指标。
목적탐토당뇨병미혈관병변환자적QT리산도(QTd)변화급기의의。방법분석50례당뇨병병발신병화[혹]시망막병변환자적체표12도련동보심전도，여52례단순당뇨병환자급50례정상인작대조。결과당뇨병신병화[혹]시망막병변조적QTd현저고우기여량조(P＜0.01)。결론①당뇨병미혈관병변가능도치심기세포손해영향심실복겁，종이사QTd증대。②당뇨병환자QTd증대시，가제시미혈관병변적발생，즉QTd가작위당뇨병미혈관병변적일항삼고지표。
Objective To study the changes of QT dispersion (QTd) of patientswith diabetic microvascular complication and its significance. Methods The 12 lead synchronic electrocardiograms of 50 diabetic patients complicated with nephropathy or with retinopathy were analysed, and 52 cases with pure diabetes as well as another 50 normal persons were involved in the study as controls. Results The QTd in diabetic patients complicated with nephropathy or with retinopathy were obviously higher than those in the other control groups(P＜0.01). Conclusion Diabetic microvasular complication may cause injury in the myocardial cell and impact the ventricular repolarization, and thus QTd is increased. The increase of QTd might indicate the occurrence of diabetic microvascular complication, and therefore QTd can be a valuable index in detecting certain diabetic microvascular complication.