CAJ | 학술논문

目的：了解羟氯喹在眼科的不良反应及其发生率。方法：选择较长期(疗程≥6 mo)服用羟氯喹的病人39例，进行眼科检查包括一些特殊的眼功能检查。结果：39例中3例(8 %)出现视野范围缩小，其中1例伴有视敏度降低。这3例服用羟氧喹累积剂量均大于100 g。结论：本观察显示羟氯喹眼科不良反应的发生可能与累积剂量有关，表现为视野改变和视敏度降低。
목적：료해간록규재안과적불량반응급기발생솔。방법：선택교장기(료정≥6 mo)복용간록규적병인39례，진행안과검사포괄일사특수적안공능검사。결과：39례중3례(8 %)출현시야범위축소，기중1례반유시민도강저。저3례복용간양규루적제량균대우100 g。결론：본관찰현시간록규안과불량반응적발생가능여루적제량유관，표현위시야개변화시민도강저。
AIM: To study the adverse reactions of hydroxychloroquine (HCQ) in ophthalmology. 　METHODS: Thirty-nine patients treated with HCQ for more than six months were performed ophthalmic examinations including some specifie retinal function tests. 　RESULTS: There were 3 patients (8%) who presented the visual fields was minified. The visual acuity of one patient was decreased. The cumulative doses of HCQ were more than 100 g in this three patients. 　CONCLUSION: The adverse reactions of HCQ in ophthalmology are related with the cumulative doses of HCQ. The expression is that the visual fields and visual acuity are decreased.