CAJ | 학술논문

目的了解丙型肝炎患者外周血B细胞和T淋巴细胞及其亚群的变化。方法应用单克隆技术测定38例丙型肝炎患者外周血B细胞和T淋巴细胞亚群的水平并以35名健康人作对照。结果丙型肝炎患者外周血B细胞数显著地高于正常人（P＜0．001）、CD３、CD４、CD４／CD８显著低于正常人（P＜0．01，P＜0．001）。结论丙型肝炎患者为一种自身免疫调节异常的疾病。
목적료해병형간염환자외주혈B세포화T림파세포급기아군적변화。방법응용단극륭기술측정38례병형간염환자외주혈B세포화T림파세포아군적수평병이35명건강인작대조。결과병형간염환자외주혈B세포수현저지고우정상인（P＜0．001）、CD３、CD４、CD４／CD８현저저우정상인（P＜0．01，P＜0．001）。결론병형간염환자위일충자신면역조절이상적질병。
Objective To study the changes of B lymphocyte，T lymphocyte，and its subgroups in peripheral blood in patients with hepatitis C．Methods B lymphocyte，T lymphocyte and its subgroups in peripheral blood in 38 patients with hepatitis C and 35 normal controls were detected with monoclonal technigue．Results The level of B lymphocyte were significanty higher than those in normal people（P＜0．001）．But CD３、CD４ and the ratio of CD４／CD８ were obviously lower（P＜0．01，P＜0．001）．Conclusion Hepatitis C is a kind of selfi-mmunity disease with abnormal immunoregulation．