CAJ | 학술논문

的：研究褪黑素(Mel)受体亚型在人胚胎肾上腺皮质的分布。方法：应用免疫组化染色检测Mel受体亚型在人胚胎肾上腺皮质的分布。结果：在人胚胎肾上腺皮质的球状带、束状带和网状带均存在Mel受体mt1（Mel1a）和MT2（Mel1b）亚型蛋白的表达，且主要分布于细胞胞质。结论：人胚胎肾上腺皮质存在Mel受体mt1和MT 2亚型。
적：연구퇴흑소(Mel)수체아형 재인배태신상선피질적분포。방법：응용면역조화염색검측Mel수체아 형재인배태신상선피질적분포。결과：재인배태신상선피질적구상대 、속상대화망상대균존재Mel수체mt1（Mel1a）화MT2（Mel1b）아형단백적표체，차주 요분포우세포포질。결론：인배태신상선피질존재Mel수체mt1화MT 2아형。
Objective: To investigate the potential role of me latonin in the adrenal cortex of human embryo. Methods:Specifi c melatonin receptors was localized and characterized in the adrenal cortex of h u man embryo by means of immunohistochemistry. Results: mt1 （Me l1a）and MT2 （Mel1b）subtype of melatonin receptors was principally localize d to cytoplasm in zona glomerulosa， fasciculata and reticularis. Conclu sion: It is possible that mt1 and MT2 subtype of melatonin receptors co-exist in the adrenal cortex of human embryo.