CAJ | 학술논문

目的：探讨高压氧联合药物治疗突发性耳聋（突聋）的疗效。方法：26例（31耳）突发性耳聋患者（HBO组）在250kPa(2.5ATA)压力下吸纯氧30min共2次，中间吸空气10min，每日1次，同时配合能量合剂、复方丹参液、低分子右旋糖酐、B族维生素、皮质激素等药物治疗，平均疗程(17.5±6.73)天。将本组疗效与单纯使用同类药物治疗的30例（33耳）突聋（非HBO组）进行比较。结果：HBO组痊愈7耳，显效6耳，有效10耳，总有效率72.4%；非HBO组痊愈5耳，显效4耳，有效7耳，总有效率48.5%，两组比较χ2=4.438，P<0.025。结论：HBO联合药物治疗突聋的效果明显优于单纯药物治疗。
목적：탐토고압양연합약물치료돌발성이롱（돌롱）적료효。방법：26례（31이）돌발성이롱환자（HBO조）재250kPa(2.5ATA)압력하흡순양30min공2차，중간흡공기10min，매일1차，동시배합능량합제、복방단삼액、저분자우선당항、B족유생소、피질격소등약물치료，평균료정(17.5±6.73)천。장본조료효여단순사용동류약물치료적30례（33이）돌롱（비HBO조）진행비교。결과：HBO조전유7이，현효6이，유효10이，총유효솔72.4%；비HBO조전유5이，현효4이，유효7이，총유효솔48.5%，량조비교χ2=4.438，P<0.025。결론：HBO연합약물치료돌롱적효과명현우우단순약물치료。
Objective:To investigate the effect of hyperbaricoxygen(HBO)combined with drugs therapy for sudden deafness(SD).Methods:Twenty-six patients(31ears)with SD were exposed to HBO[pure oxygen breathing at 250 kPa(2.5ATA)absolute for 30min,twice,with a 10 min air breathing breath in the chamber，once a day],meanwhile they were also given commonly used drugs(energy mixture,injectio salvia miltiorrhiza Co, dextran 40,vitamin B group and corticoids)for(17.5±6.73)days.Thirty patients(33 ears)for comparison(non-HBO group)were treated only by the above-mentioned drug without HBO.Results:HBO group:7 ears were cured,6 ears markedly improved,10 ears improved;non-HBO group:5 ears were cured,4 ears markedly improved,7 ears improved.The overall effective rate in HBO group(72.4%)was higher than that in non-HBO group(48.5%)(χ2=4.438,P<0.025).Conclusion:The therapeutic effect of HBO combined with drugs for SD is significantly better than that of simple drug treatment without HBO.