CAJ | 학술논문

目的调查核实山东省碘缺乏病高危地区,为进一步实施应急补碘措施提供参考依据.方法 2008年在山东省碘缺乏病高危地区济南市历城区和寿光市,查阅既往卫生部门统计的克汀病的发病记录;各抽取3个乡镇,每个乡镇抽取2所学校,每所学校抽取40名8～10岁儿童作为观察对象,采用触诊、B超法检测甲状腺,并采集尿样检测尿碘(砷铈催化分光光度法);每个乡镇抽取2个村,每个村抽取20名18～40岁育龄妇女作为观察对象,检测尿碘和家庭食用盐含碘量(直接滴定法).结果自1995年来,未发现克汀病新发病例和疑似病例;济南市历城区和寿光市儿童触诊、B超法甲状腺肿大率分别为7.5%(18/241)、6.2%(15/241),5.0%(13/259)、1.2%(3/259);采集尿样分别为240、249份,尿碘中位数分别为226.3、282.7μg/L.采集育龄妇女尿样各120份,尿碘中位数分别为187.2、321.7μg/L;采集盐样各120份,非碘盐分别为8份和2份,碘盐合格率均为100%.结论济南市历城区和寿光市目前尚不需要启动应急补碘措施,但需进一步加强盐业监督和稽查,彻底消除非碘盐和不合格碘盐的危害.
목적 조사핵실산동성전결핍병고위지구,위진일보실시응급보전조시제공삼고의거.방법 2008년재산동성전결핍병고위지구제남시력성구화수광시,사열기왕위생부문통계적극정병적발병기록;각추취3개향진,매개향진추취2소학교,매소학교추취40명8～10세인동작위관찰대상,채용촉진、B초법검측갑상선,병채집뇨양검측뇨전(신시최화분광광도법);매개향진추취2개촌,매개촌추취20명18～40세육령부녀작위관찰대상,검측뇨전화가정식용염함전량(직접적정법).결과 자1995년래,미발현극정병신발병례화의사병례;제남시력성구화수광시인동촉진、B초법갑상선종대솔분별위7.5%(18/241)、6.2%(15/241),5.0%(13/259)、1.2%(3/259);채집뇨양분별위240、249빈,뇨전중위수분별위226.3、282.7μg/L.채집육령부녀뇨양각120빈,뇨전중위수분별위187.2、321.7μg/L;채집염양각120빈,비전염분별위8빈화2빈,전염합격솔균위100%.결론 제남시력성구화수광시목전상불수요계동응급보전조시,단수진일보가강염업감독화계사,철저소제비전염화불합격전염적위해.
Objective To survey the highly risk iodine deficiency regions of Shandong Province and to provide reference basis for further executing urgent iodine supply. Methods The annual document of cretinism in Licheng District in Jinan City and Shouguang City, the two iodine deficiency regions, were referred. Forty children aged 8-10 years of 2 targeted schools from 3 towns out of every targeted region underwent palpation, ultrasonography and As3+-Ce4+catalyzing speetrophotometry for ultra iodine examination. Twenty women aged 18-40 years from 2 villages sampled from every targeted town received ultra iodine examination and edible salt examination of iodine with direct titration. Results No new cretinism and suspected cretinism was found since 1995 in the regions. The goiter rates of children of the two regions detected with palpation and ultrasonography were 7.5% (18/241),6.2% (15/241) and 5.0% (13/259), 1.2% (3/259), respectively. Two hundred forty and 249 urine samples were respectively collected in school children, in which the median urinary iodine was 226.3,282.7 μg/L. One hundred twenty urine samples were respectively collected from the two group of women, resulting a median urinary iodine of 187.2,321.7 μg/L. Eight and 2 salt samples were free of iodine in 120 salt samples collected each region, respectively. The rate of qualified iodized salt was 100%. Conclusions It is not necessary to urgently implement iodine supply in Shouguang City and Licheng District. However, reinforcement of supervise on salt industry and eliminating the hazard from non-iodized and disqualified iodized salt remains in need.