CAJ | 학술논문

采用免疫荧光技术和流式细胞仪测定对照组及2型糖尿病患者组单核细胞和中性粒细胞CD11b的表达,发现合并大血管病变患者的单核细胞和中性粒细胞CD1b水平均明显高于不合并大血管病变的2型糖尿病患者[3.85±1.46对2.88±0.92,6.36(4.58-9.79)对4.23(3.70-4.83),均P<0.01],单核细胞CD11b、中性粒细胞CD11b高表达可能是2型糖尿病大血管病变发生的独立危险因素.
채용면역형광기술화류식세포의측정대조조급2형당뇨병환자조단핵세포화중성립세포CD11b적표체,발현합병대혈관병변환자적단핵세포화중성립세포CD1b수평균명현고우불합병대혈관병변적2형당뇨병환자[3.85±1.46대2.88±0.92,6.36(4.58-9.79)대4.23(3.70-4.83),균P<0.01],단핵세포CD11b、중성립세포CD11b고표체가능시2형당뇨병대혈관병변발생적독립위험인소.
The expression of CD11b on monocytes and neutrophils were measured by direct immunofluorescence techiques and flow cytometry in controls and type 2 diabetic patients.CD11b expression on monocyte and neutrophil in diabetic patients with macroangiopathy was higher than that in cases without macroangiopathy [3.85±1.46 vs 2.88±0.92,6.36 (4.58-9.79) vs 4.23 (3.70-4.83),both P<0.01].Monocyte CD11b and neutrophil CD11b might be independent risk factors of macroangiopathy in type 2 diabetes mellitus.