CAJ | 학술논문

目的探讨腔隙性脑梗死患者介入治疗术后认知的功能变化特点.方法 43例伴颈动脉狭窄的腔隙性脑梗死患者分别于术前及术后1个月、6个月、12个月进行神经心理学测验,并与41例正常人比较.结果与对照组比较,治疗组患者术前简易智能状态检查量表( MMSE)评分[(26.33±1.94)分]、记忆力、执行能力均降低,差异有统计学意义(P＜0.05或P＜0.01).与术前比较,治疗组患者MMSE评分术后1月[(27.17 ±2.15)分]、术后6月[(27.78±2.12)分]、术后12月[(28.15±1.98)分],及记忆力、执行能力大都明显改善,差异有统计学意义(P＜0.05或P＜0.01).结论腔隙性脑梗死患者急性期(发病1周内)大部分认知功能损害较重,介入治疗12月后大都恢复正常,其机制可能与慢性脑供血不足的改善有关.
목적 탐토강극성뇌경사환자개입치료술후인지적공능변화특점.방법 43례반경동맥협착적강극성뇌경사환자분별우술전급술후1개월、6개월、12개월진행신경심이학측험,병여41례정상인비교.결과 여대조조비교,치료조환자술전간역지능상태검사량표( MMSE)평분[(26.33±1.94)분]、기억력、집행능력균강저,차이유통계학의의(P＜0.05혹P＜0.01).여술전비교,치료조환자MMSE평분술후1월[(27.17 ±2.15)분]、술후6월[(27.78±2.12)분]、술후12월[(28.15±1.98)분],급기억력、집행능력대도명현개선,차이유통계학의의(P＜0.05혹P＜0.01).결론 강극성뇌경사환자급성기(발병1주내)대부분인지공능손해교중,개입치료12월후대도회복정상,기궤제가능여만성뇌공혈불족적개선유관.
Objective To explore the characteristics of the cognitive changes in patients with lacunar infarction(LI) after carotid artery stenting(CAS).Methods Neuropsychological tests were conducted in 43 patients with LI and carotid stenosis before and 1 month,6 months,12 months after CAS and the scores were compared with those of 41 healthy cases.Results Compared with control group,MMSE scores ( 26.33 ± 1.94),memory and executive function in therapy group lowered obviously.There was statistical difference (P＜ 0.05 or P＜ 0.01 ).Compared with before CAS,MMSE scores of 1 month (27.17±2.15),6 months (27.17 ±2.15),12 months (28.15±1.98) after CAS,memory and executive function in therapy group were all better obviously.There was statistical difference (P＜0.05 or P＜0.01).Conclusion In acute stage of patients with LI (with in 1 week),most cognitive impairment was severe. Most cognition disorders was improved to normal level 12 months after CAS.The mechanism may be associated with the improvement of chronic cerebral insufficiency.