CAJ | 학술논문

目的研究健康成年人高通噪声掩蔽听性脑干反应(又称为耳蜗积水掩蔽分析程序,the cochlear hydrops analysis masking procedure,CHAMP)的特点,探讨CHAMP各参数在诊断膜迷路积水中的应用价值.方法应用Bio-logic听性诱发电位系统对20名(40耳,其中男女各10名)耳科正常人记录由6种声信号所诱发的听性脑干反应(auditory brainstem response,ABR),包括:单独使用短声及截断点分别为8、4、2、1、0.5 kHz同侧高通滤过粉红噪声(high-pass masking pink noise)掩蔽下的短声信号.结果高通滤过粉红噪声掩蔽下的短声所诱发的ABR V波潜伏期较短声ABR长,短声+8、4、2、1、0.5 kHz高通滤过粉红噪声的V波潜伏期延迟平均((x)±s,下同)分别为(0.30±0.18)、(0.97 ±0.43)、(1.65±0.64)、(3.21±0.56)、(4.66±0.37)ms.短声+0.5 kHz高通滤过粉红噪声诱发的ABR与短声ABR的复合振幅比为0.95 ±0.11.结论对于膜迷路积水,CHAMP可能是一种很有前景的诊断方法,V波潜伏期延迟可作为判定CHAMP正常与否的标准,但复合振幅比的特异性有待进一步验证.
목적 연구건강성년인고통조성엄폐은성뇌간반응(우칭위이와적수엄폐분석정서,the cochlear hydrops analysis masking procedure,CHAMP)적특점,탐토CHAMP각삼수재진단막미로적수중적응용개치.방법 응용Bio-logic은성유발전위계통대20명(40이,기중남녀각10명)이과정상인기록유6충성신호소유발적은성뇌간반응(auditory brainstem response,ABR),포괄:단독사용단성급절단점분별위8、4、2、1、0.5 kHz동측고통려과분홍조성(high-pass masking pink noise)엄폐하적단성신호.결과 고통려과분홍조성엄폐하적단성소유발적ABR V파잠복기교단성ABR장,단성+8、4、2、1、0.5 kHz고통려과분홍조성적V파잠복기연지평균((x)±s,하동)분별위(0.30±0.18)、(0.97 ±0.43)、(1.65±0.64)、(3.21±0.56)、(4.66±0.37)ms.단성+0.5 kHz고통려과분홍조성유발적ABR여단성ABR적복합진폭비위0.95 ±0.11.결론 대우막미로적수,CHAMP가능시일충흔유전경적진단방법,V파잠복기연지가작위판정CHAMP정상여부적표준,단복합진폭비적특이성유대진일보험증.
Objective To study the characteristic of the cochlear hydrops analysis masking procedure ( CHAMP) in normal adults, and to evaluate the diagnostic values of its parameters for logic auditory evoked potential system: clicks presented alone (unmasked condition) and clicks presented with ipsilateral pink noise high-pass filtered at 8 , 4, 2, 1, and 0. 5 kHz respectively. Results The wave V latency of ABR to the high-pass masking pink noise clicks were longer than ABR to clicks alone. The latency delays of wave V for clicks presented with ipsilateral pink noise high-pass filtered at 8 , 4, 2, 1, and 0.5 kHz compared to clicks alone were (0.30 ±0.18), (0.97 ±0.43), (1.65 ±0.64), (3.21 ±0.56),(4. 66 ± 0. 37 ) ms respectively. The complex amplitude ratio between ABR to click + 0. 5 kHz high-pass noise and click alone was 0.95 ±0.11. Conclusions CHAMP is a promising diagnostic method for membranous labyrinth hydrops, and the latency delay of wave V might be used as the normal criterion. The specificity of the complex amplitude ratio need furthur evaluation in clinical work.