CAJ | 학술논문

目的寻找一种快捷、高效的应急治疗哮喘的方法。方法将50例中、重度哮喘急性发作患儿随机分为三组。A组：超声雾化吸入0.5％备劳特液每次50μg/kg，加用地塞米松5mg，雾化吸入15min；B组：6L/min氧驱动雾化吸入0.5％备劳特液每次50μg/kg，加用地塞米松5mg，雾化吸入10min；C组：静滴氨茶碱每次3～5mg/kg，加用琥珀酸氢考每次5.0mg/kg，同时配合吸氧。观察各组临床症状改善情况，测定治疗前、后15min最大呼气流速(PEF)。结果①各组临床症状改善情况：A组改善率21.4％(3/14)；B组改善率85.0％(17/20)；C组改善率81.3％(13/16)。②各组治疗前后△PEF(L/min)变化：A组11.714±7.549，B组41.100±2.618，C组40.875±19.418；③各组PEF变异率＞15％情况：A组阳性率7.1％(1/14)，B组阳性率65.0％(13/20)，C组阳性率68.8％(11/16)。B、C两组临床症状改善和△PEF改变优于A组(P＜0.01)。结论 6L/min氧驱动雾化吸入治疗中、重度哮喘急性发作是一个快速、高效的方法。
목적심조일충쾌첩、고효적응급치료효천적방법。방법장50례중、중도효천급성발작환인수궤분위삼조。A조：초성무화흡입0.5％비로특액매차50μg/kg，가용지새미송5mg，무화흡입15min；B조：6L/min양구동무화흡입0.5％비로특액매차50μg/kg，가용지새미송5mg，무화흡입10min；C조：정적안다감매차3～5mg/kg，가용호박산경고매차5.0mg/kg，동시배합흡양。관찰각조림상증상개선정황，측정치료전、후15min최대호기류속(PEF)。결과①각조림상증상개선정황：A조개선솔21.4％(3/14)；B조개선솔85.0％(17/20)；C조개선솔81.3％(13/16)。②각조치료전후△PEF(L/min)변화：A조11.714±7.549，B조41.100±2.618，C조40.875±19.418；③각조PEF변이솔＞15％정황：A조양성솔7.1％(1/14)，B조양성솔65.0％(13/20)，C조양성솔68.8％(11/16)。B、C량조림상증상개선화△PEF개변우우A조(P＜0.01)。결론 6L/min양구동무화흡입치료중、중도효천급성발작시일개쾌속、고효적방법。
Objective To search for a quick and effective therapy for acute bronchial asthma in children. Methods Group A:ultrasonic nebulizer inhaler 0.5% berotec,50μg/kg each time and dexamethasone 5mg, 15 minutes. Group B:6L/min oxygen nebulizer inhaler 0.5% berotec,50μg/kg each time and dexamethasone 5mg, 10minutes. Group C:intravenous drip aminophylline 3～5mg/kg each time and hydrocortisone sodium succinate 5mg/kg,inhale oxygen. Results (1) Symptom improve rate in each group:Group A,21.4% (3/14). Group B,85.0% (17/20). Group C,81.3% (13/16). (2) Every group △PEF variant: Group A:11.714±7.549; Group B:41.100±2.618; Group C: 40.875±19.418. (3) Every group PEF variation rate＞15%:Group A positive rate:7.1% (1/14). Group B positive rate:65.0% (13/20). Group C positive rate:68.8% (11/16). Group B and C were better than Group A(P＜0.01). Conclusion 6L/min oxygen nebulizer inhalation is a quick and effective treatment.