科学通报（英文版）
科學通報（英文版）
과학통보（영문판）
CHINESE SCIENCE BULLETIN
2005年
8期
752-757
,共6页
magnetic targeted drug%zinc aluminum layered double hydroxide%captopril%5-aminosalicylic acid%coprecipitation%core- shell structure
The synthesis by direct coprecipitation and characterization of captopril (Cpl) and 5-aminosalicylic acid (5-ASA) intercalated ZnAl layered double hydroxides coated on MgFe2O4 magnetic core particles are reported. Powder XRD analysis shows the well-defined crystallite structure of the composites. TEM and XPS results reveal that a core-shell structure involving a drug-LDHs layer coated on MgFe2O4 particles is formed through Zn-O-Mg and/or Al-O-Mg linkages. VSM measurements demonstrate that the novel magnetic drug-inorganic composites possess considerable magnetization.
