中国医学影像技术
中國醫學影像技術
중국의학영상기술
CHINESE JOURNAL OF MEDICAL IMAGING TECHNOLOGY
2009年
7期
1131-1133
,共3页
杨秀军%任其乐%李巍%胥文娟
楊秀軍%任其樂%李巍%胥文娟
양수군%임기악%리외%서문연
股骨头坏死%模型,动物%体层摄影术,X线计算机%灌注%减影技术
股骨頭壞死%模型,動物%體層攝影術,X線計算機%灌註%減影技術
고골두배사%모형,동물%체층섭영술,X선계산궤%관주%감영기술
Femoral head necrosis%Models,animal%Tomography,X-ray computed%Perfusion%Subtraction technique
目的 探讨减影计算机体层摄影灌注成像(sCTP)技术及观察犬缺血性股骨头坏死的方法与可行性.方法 对16只犬于旋股动脉内结扎术前后行股骨头CTP扫描,以观察股骨头坏死.在AW 4.2工作站利用减影软件对CTP源影像进行减影处理,再以Perfusion 3软件对减影图像数据和源影像数据分别作血流量(BF)、血容量(BV)、平均通过时间(MTT)色阶图分析并测量兴趣区其参数值. 结果 ①对CTP源影像减影所得新图像数据行灌注成像软件后处理成功率为100%,均获得了BF、BV、MTT色阶图及其数值,sCTP后处理时间约需1～5 h;②sCTP提供的BF、BV、MTT数值及色阶图能对比显示股骨头坏死,常规骨CTP难以揭示这些改变. 结论 sCTP技术可行,适用于骨的CT灌注成像、定量诊断骨坏死.
目的 探討減影計算機體層攝影灌註成像(sCTP)技術及觀察犬缺血性股骨頭壞死的方法與可行性.方法 對16隻犬于鏇股動脈內結扎術前後行股骨頭CTP掃描,以觀察股骨頭壞死.在AW 4.2工作站利用減影軟件對CTP源影像進行減影處理,再以Perfusion 3軟件對減影圖像數據和源影像數據分彆作血流量(BF)、血容量(BV)、平均通過時間(MTT)色階圖分析併測量興趣區其參數值. 結果 ①對CTP源影像減影所得新圖像數據行灌註成像軟件後處理成功率為100%,均穫得瞭BF、BV、MTT色階圖及其數值,sCTP後處理時間約需1～5 h;②sCTP提供的BF、BV、MTT數值及色階圖能對比顯示股骨頭壞死,常規骨CTP難以揭示這些改變. 結論 sCTP技術可行,適用于骨的CT灌註成像、定量診斷骨壞死.
목적 탐토감영계산궤체층섭영관주성상(sCTP)기술급관찰견결혈성고골두배사적방법여가행성.방법 대16지견우선고동맥내결찰술전후행고골두CTP소묘,이관찰고골두배사.재AW 4.2공작참이용감영연건대CTP원영상진행감영처리,재이Perfusion 3연건대감영도상수거화원영상수거분별작혈류량(BF)、혈용량(BV)、평균통과시간(MTT)색계도분석병측량흥취구기삼수치. 결과 ①대CTP원영상감영소득신도상수거행관주성상연건후처리성공솔위100%,균획득료BF、BV、MTT색계도급기수치,sCTP후처리시간약수1～5 h;②sCTP제공적BF、BV、MTT수치급색계도능대비현시고골두배사,상규골CTP난이게시저사개변. 결론 sCTP기술가행,괄용우골적CT관주성상、정량진단골배사.
Objective To investigate the technical protocols and feasibility of subtraction computed tomography perfusion imaging (sCTP) on observation of ischemic necrosis of femoral head (ANFH) on dog. Methods Sixteen laboratory canines underwent CT perfusion imaging (CTP) of femoral head before and after selective femoral circumflex artery embolization, and ANFH were observed. Then new sequence imaging data, created by sources imaging of CT perfusion scan using subtraction software, were analyzed at workstation (AW 4.2) with CT perfusion 3 analysis program, and data of sCTP were obtained. The parametric maps and indexes of capillary-level hemodynamics including blood volume (BV), blood flow (BF) and mean transit time (MTT) of CTP and sCTP were compared. Results ①The technical success rate of sCTP post-processing created from CTP sources imaging data was 100%. The values and mappings of BF, BV and MTT of region of interest (ROI) were all obtained from subtraction sequence images data. The post-processing time of sCTP was about 1-5 h. ② sCTP depicted ANFH well, though the values and mappings of BF, BV and MTT were different from those obtained with conventional bone CTP. Conclusion sCTP can be generated with subtraction and perfusion analysis program and techniques. It can be applied to bone CT perfusion imaging and early quantitative diagnosis of necrosis.
