中华麻醉学杂志
中華痳醉學雜誌
중화마취학잡지
CHINESE JOURNAL OF ANESTHESIOLOGY
2011年
10期
1200-1202
,共3页
曲马朵%二异丙酚%哌啶类%药物释放系统
麯馬朵%二異丙酚%哌啶類%藥物釋放繫統
곡마타%이이병분%고정류%약물석방계통
Tramadol%Propofol%Piperidines%Drug delivery systems
目的 评价术前口服曲马多缓释片对老年患者无痛肠镜诊疗术中靶控输注异丙酚复合瑞芬太尼麻醉效果的影响.方法 拟行无痛肠镜诊疗术患者60例,年龄≥65岁,ASA分级Ⅰ或Ⅱ级,采用随机数字表法,将患者随机分为2组(n=30):对照组(C组)和曲马多组(T组),T组术前2h口服曲马多缓释片100 mg.两组均采用靶控输注异丙酚复合瑞芬太尼麻醉.于麻醉诱导前、肠镜至回盲瓣、术毕时记录SP、DP、HR、SpO2,记录麻醉诱导时间、诊疗操作时间、苏醒时间、恢复时间、不良事件发生情况及异丙酚和瑞芬太尼用量.结果 两组各时点血液动力学指标、麻醉诱导时间、诊疗操作时间、苏醒时间、恢复时间、不良事件发生率及异丙酚和瑞芬太尼用量比较差异无统计学意义(P＞0.05).结论 术前口服曲马多缓释片100 mg可安全用于老年患者无痛肠镜诊疗术,但不能有效增强靶控输注异丙酚复合瑞芬太尼的麻醉效果.
目的 評價術前口服麯馬多緩釋片對老年患者無痛腸鏡診療術中靶控輸註異丙酚複閤瑞芬太尼痳醉效果的影響.方法 擬行無痛腸鏡診療術患者60例,年齡≥65歲,ASA分級Ⅰ或Ⅱ級,採用隨機數字錶法,將患者隨機分為2組(n=30):對照組(C組)和麯馬多組(T組),T組術前2h口服麯馬多緩釋片100 mg.兩組均採用靶控輸註異丙酚複閤瑞芬太尼痳醉.于痳醉誘導前、腸鏡至迴盲瓣、術畢時記錄SP、DP、HR、SpO2,記錄痳醉誘導時間、診療操作時間、囌醒時間、恢複時間、不良事件髮生情況及異丙酚和瑞芬太尼用量.結果 兩組各時點血液動力學指標、痳醉誘導時間、診療操作時間、囌醒時間、恢複時間、不良事件髮生率及異丙酚和瑞芬太尼用量比較差異無統計學意義(P＞0.05).結論 術前口服麯馬多緩釋片100 mg可安全用于老年患者無痛腸鏡診療術,但不能有效增彊靶控輸註異丙酚複閤瑞芬太尼的痳醉效果.
목적 평개술전구복곡마다완석편대노년환자무통장경진료술중파공수주이병분복합서분태니마취효과적영향.방법 의행무통장경진료술환자60례,년령≥65세,ASA분급Ⅰ혹Ⅱ급,채용수궤수자표법,장환자수궤분위2조(n=30):대조조(C조)화곡마다조(T조),T조술전2h구복곡마다완석편100 mg.량조균채용파공수주이병분복합서분태니마취.우마취유도전、장경지회맹판、술필시기록SP、DP、HR、SpO2,기록마취유도시간、진료조작시간、소성시간、회복시간、불량사건발생정황급이병분화서분태니용량.결과 량조각시점혈액동역학지표、마취유도시간、진료조작시간、소성시간、회복시간、불량사건발생솔급이병분화서분태니용량비교차이무통계학의의(P＞0.05).결론 술전구복곡마다완석편100 mg가안전용우노년환자무통장경진료술,단불능유효증강파공수주이병분복합서분태니적마취효과.
Objective To evaluate the effect of oral tramadol controlled release tablets premedication on the efficacy of anesthesia with target-controlled infusion (TCI)of propofol and remifentanil for painless colonoscopy in elderly patients.Methods Sixty ASA Ⅰ or Ⅱ patients,aged≥ 65 yr,undergoing painless colonoscopy,were randomly divided into 2 groups ( n =30 each): control group (group C) and tramadol group(group T).In group T tramadol controlled-release tablet 100 mg was administered orally at 2 h before operation.Anesthesia was induced and maintained with TCI of propofol and remifentanil.SP,DP,HR and SpO2 were recorded before induction,at the time to reach the ileocecal valve and at the end of operation.The induction time,duration of operation,emergence time,recovery time,adverse events and the amount of propofol and remifentanil consumed were recorded.Results There was no significant difference in hemodynamics parameters,induction time,duration of operation,emergence time,recovery time,adverse events and the amount of propofol and remifentanil consumed between the two groups (P ＞ 0.05 ).Conclusion Oral tramadol controlled release tablets 100 mg premedication can be safely used in painless colonoscopy in elderly patients,however,tramadol can not enhance the efficacy of anesthesia with TCI of propofol and remifentanil.
