北京医学
北京醫學
북경의학
BEIJING MEDICAL JOURNAL
2010年
4期
321-322,325
,共3页
陈民才%冯学胜%宋丽杰%杨玉兰%冯谦%王全立
陳民纔%馮學勝%宋麗傑%楊玉蘭%馮謙%王全立
진민재%풍학성%송려걸%양옥란%풍겸%왕전립
成分献血者%血小板功能%血液质量
成分獻血者%血小闆功能%血液質量
성분헌혈자%혈소판공능%혈액질량
Platelet donors%Platelet function%Quality of platelets
目的 分析捐献血小板人群的献血间隔和频采后的血小板功能状态,确保血小板的采集质量和献血者的自身健康.方法 分别检测固定频采血小板捐献者(2次/月)和正常固定献血者(1次/月)的红细胞计数(RBC)、血红蛋白(Hb)、白细胞计数(WBC)、平均红细胞体积(MCV)、平均血红蛋白含量(MCH)、平均血红蛋白浓度(MCHC)、红细胞宽度标准差(RDW-SD)、血小板计数(Plt)、平均血小板体积(MPV)、血小板分布宽度(PDW)、体外血小板聚集率等指标并进行比较.结果 RBC、Hb、WBC、MCV、MCHC、RDW-SD两组之间比较无显著性差异,Plt[(339.36±30.24)×109/L vs.(248.25±20.61)×109/L,P＜0.0001]、MPV[(8.44±0.52)fl vs.(8.65±0.32)fl,P＜0.001]、PDW[(15.52±1.13)%vs.(13.96±0.45)%.P＜0.0001]及血小板体外聚集功能有显著性差异.结论 频采者虽然有较高的Plt计数,但血小板的功能低于正常间隔血小板捐献者.因此,为保障血小板采集质量,应尽可能避免频繁采集血小板.
目的 分析捐獻血小闆人群的獻血間隔和頻採後的血小闆功能狀態,確保血小闆的採集質量和獻血者的自身健康.方法 分彆檢測固定頻採血小闆捐獻者(2次/月)和正常固定獻血者(1次/月)的紅細胞計數(RBC)、血紅蛋白(Hb)、白細胞計數(WBC)、平均紅細胞體積(MCV)、平均血紅蛋白含量(MCH)、平均血紅蛋白濃度(MCHC)、紅細胞寬度標準差(RDW-SD)、血小闆計數(Plt)、平均血小闆體積(MPV)、血小闆分佈寬度(PDW)、體外血小闆聚集率等指標併進行比較.結果 RBC、Hb、WBC、MCV、MCHC、RDW-SD兩組之間比較無顯著性差異,Plt[(339.36±30.24)×109/L vs.(248.25±20.61)×109/L,P＜0.0001]、MPV[(8.44±0.52)fl vs.(8.65±0.32)fl,P＜0.001]、PDW[(15.52±1.13)%vs.(13.96±0.45)%.P＜0.0001]及血小闆體外聚集功能有顯著性差異.結論 頻採者雖然有較高的Plt計數,但血小闆的功能低于正常間隔血小闆捐獻者.因此,為保障血小闆採集質量,應儘可能避免頻繁採集血小闆.
목적 분석연헌혈소판인군적헌혈간격화빈채후적혈소판공능상태,학보혈소판적채집질량화헌혈자적자신건강.방법 분별검측고정빈채혈소판연헌자(2차/월)화정상고정헌혈자(1차/월)적홍세포계수(RBC)、혈홍단백(Hb)、백세포계수(WBC)、평균홍세포체적(MCV)、평균혈홍단백함량(MCH)、평균혈홍단백농도(MCHC)、홍세포관도표준차(RDW-SD)、혈소판계수(Plt)、평균혈소판체적(MPV)、혈소판분포관도(PDW)、체외혈소판취집솔등지표병진행비교.결과 RBC、Hb、WBC、MCV、MCHC、RDW-SD량조지간비교무현저성차이,Plt[(339.36±30.24)×109/L vs.(248.25±20.61)×109/L,P＜0.0001]、MPV[(8.44±0.52)fl vs.(8.65±0.32)fl,P＜0.001]、PDW[(15.52±1.13)%vs.(13.96±0.45)%.P＜0.0001]급혈소판체외취집공능유현저성차이.결론 빈채자수연유교고적Plt계수,단혈소판적공능저우정상간격혈소판연헌자.인차,위보장혈소판채집질량,응진가능피면빈번채집혈소판.
Objective To compare platelet function between regular multi platelet donation donors (2 times/month) and regular normal donors (1 time/month), and assess specific parameters to make a rational analysis of the donation interval to ensure the quality of platelets used for clinical purposes. Methods RBC, HGB, MCV, MCHC, RDW-SD, PLT,MPV, PDW and platelet aggregation rate were used to compare donations from regular multi platelet donors and regular normal donors. Results The indices of RBC, WBC, HGH, MCV, average red cells and RDW-SD showed no significant differences between the two regular donor groups. Significant differences between the two donor groups were detected in PLT, MPV, PDW indices and the platelet aggregation assay. Conclusions Despite the relatively high platelet counts among regular multi platelet donations donors, their platelet's ability to aggregate in vitro decrease compared with that of regular normal donors. It is recommended to collect platelet from regular normal donors to ensure the quality of the blood platelet donations
