CAJ | 학술논문

目的调查云南腾冲地区人群中虫媒病毒抗体,以了解当地虫媒病毒流行情况.方法应用间接免疫荧光试验(IFA)对72例不明发热患者血清中虫媒病毒抗体进行测定,同时选取37名健康体检者作为对照组.结果发热患者血清中乙型脑炎病毒(JEV)、西尼罗病毒(WNV)、基孔肯雅病毒(CHK)、辛德毕斯病毒(SIN)和西部马脑炎病毒(WEE) IgG抗体阳性率依次为41.67％、50.00％、2.78％、1.39％、0.00％；正常人群血清JEV、WNV抗体阳性率分别为18.92％、32.43％,CHK、SIN、WEE IgG抗体均未检出.21例JEV、WNV抗体均为阳性样本的几何平均滴度(GMRT)分别为1:28和1:31.结论该地区存在着黄病毒和甲病毒感染,还可能存在着其他虫媒病毒感染.
목적 조사운남등충지구인군중충매병독항체,이료해당지충매병독류행정황.방법 응용간접면역형광시험(IFA)대72례불명발열환자혈청중충매병독항체진행측정,동시선취37명건강체검자작위대조조.결과 발열환자혈청중을형뇌염병독(JEV)、서니라병독(WNV)、기공긍아병독(CHK)、신덕필사병독(SIN)화서부마뇌염병독(WEE) IgG항체양성솔의차위41.67％、50.00％、2.78％、1.39％、0.00％；정상인군혈청JEV、WNV항체양성솔분별위18.92％、32.43％,CHK、SIN、WEE IgG항체균미검출.21례JEV、WNV항체균위양성양본적궤하평균적도(GMRT)분별위1:28화1:31.결론 해지구존재착황병독화갑병독감염,환가능존재착기타충매병독감염.
Objective To study the prevalence rate of arbovirus antibodies in human being,and to understand the epidemic situation of arbovirus in Tengchong,Yunnan Province.Methods Serum antibodies in 72 cases with fever and 37 healthy people as control were detected by immunofluorescence assay.Results The positive rates of antibodies against Japanese encephalitis virus(JEV),West nile virus(WNV),Chikungunya virus(CHK),Sindbis virus(SIN),Western equine encephalomyelitis virus(WEE) in these patients were 41.67％,50.00％,2.78％,1.39％ and 0.00％,respectively.The positive rates of antibodies against JEV and WNV in healthy people were 18.92％ and 32.43％,respectively.The geometric mean reciprocal titers(GMRT) in21 co-positives of JEV and WNV were 1:28 and 1:31,respectively.Conclusions The result shows that there are Flavivirus,Alphavirus and other Arbovirtus infection in Tengchong,Yunnan Province.