CAJ | 학술논문

目的:探讨参松养心胶囊对冠心病室性期前收缩的临床疗效和安全性. 方法:对符合纳入标准的 206例门诊或住院患者,采用随机双盲双模拟对照,按 1:1随机分为治疗组 103例,给予参松养心胶囊( 4粒, 3次 /d),对照组 103例给予心律宁片( 2片, 3次 /d). 4周后进行室性期前收缩、主要症状、心电图等疗效及毒副作用的评估. 结果:治疗组室性期前收缩显效率 35.0%( 36/103),总有效率 69.0%( 71/103),明显优于对照组显效率 18.4%( 19/103)与总有效率 48.5%( 50/103)( Z=- 3.261, P=0.001). 结论:参松养心胶囊治疗冠心病室性期早搏明显优于心律宁片,未见对血、尿、便常规,肝、肾功能等的不良影响.
목적:탐토삼송양심효낭대관심병실성기전수축적림상료효화안전성. 방법:대부합납입표준적 206례문진혹주원환자,채용수궤쌍맹쌍모의대조,안 1:1수궤분위치료조 103례,급여삼송양심효낭( 4립, 3차 /d),대조조 103례급여심률저편( 2편, 3차 /d). 4주후진행실성기전수축、주요증상、심전도등료효급독부작용적평고. 결과:치료조실성기전수축현효솔 35.0%( 36/103),총유효솔 69.0%( 71/103),명현우우대조조현효솔 18.4%( 19/103)여총유효솔 48.5%( 50/103)( Z=- 3.261, P=0.001). 결론:삼송양심효낭치료관심병실성기조박명현우우심률저편,미견대혈、뇨、편상규,간、신공능등적불량영향.
OBJECTIVE: To discuss the clinical therapeutic effectiveness and safety of Ginseng-spikenard heart nourishing capsule to ventricular extrasystole in coronary heart disease. METHODS:206 cases of patients accorded with inclusive criteria from outpatient or inpatient department were randomly allocated with randomly double blind double analogue into therapy group with 103 cases and treated with the capsule(4 capsules,3 times a day). 103 cases were allocated into control group and treated with Xinluning(2 tablets,3 times a day). Therapeutic effectiveness and toxic side effects on ventricular extrasystole,main symptoms,and electrocardiogram were assessed after 4 weeks. RESULTS:The effective rate of ventricular extrasystole in the therapy group was 35.0% (36/103) and the total effective rate was 69.0% (71/103), which were markedly higher than those of the control group[18.4% (19/103) and 48.5% (50/103) respectively](Z=3.261,P=0.001). CONCLUSION:The therapeutic effectiveness of the capsule in the treatment of ventricular extrasystole in coronary heart disease was obviously better than that of Xinluning,and the side effects was not found in the routine test of blood,urine,stool and liver,and kidney functions.