中华老年心脑血管病杂志
中華老年心腦血管病雜誌
중화노년심뇌혈관병잡지
CHINESE JOURNAL OF GERIATRIC CARDIOVASCULAR AND CEREBROVASCULAR DISEASES
2009年
8期
581-583
,共3页
孙颖%路方红%刘振东%孙尚文%赵颖馨%金世宽%王舒健
孫穎%路方紅%劉振東%孫尚文%趙穎馨%金世寬%王舒健
손영%로방홍%류진동%손상문%조영형%금세관%왕서건
高血压%动脉硬化%血压监测,便携式%心率%年龄因素
高血壓%動脈硬化%血壓鑑測,便攜式%心率%年齡因素
고혈압%동맥경화%혈압감측,편휴식%심솔%년령인소
hypertension%arteriosclerosis%blood pressure monitoring,ambulatory%heart rate%age factors
目的 探讨老老年人群动态血压参数与动脉僵硬度的相关性.方法 筛选年龄≥80岁的老老年人238例,以血压≥160/95 mm Hg(1 mm Hg=0.133 kPa)为标准,分为高血压组(134例)和对照组(104例),并进行臂-踝脉搏传导速度(baPWV)和24 h动态血压监测.用Pearson分析动态血压各参数与动脉僵硬度的相关性.结果 高血压组baPWV高于对照组(P<0.05).高血压组偶测收缩压,24 h、昼间和夜间收缩压,舒张压、脉压.收缩压负荷及舒张压负荷均高于对照组,夜间收缩压下降率、舒张压下降率低于对照组,差异有统计学意义(P<0.05,P<0.01).baPWV与偶测血压;24 h收缩压、舒张压、脉压;昼间收缩压、舒张压、脉压、心率;夜间收缩压、舒张压、脉压;收缩压负荷、舒张压负荷呈正相关(P<0.05,P<0.01),而与夜间收缩压下降率呈负相关(P<0.01).结论 高血压是老老年人群动脉僵硬度增加的一个重要因素,动脉僵硬度与动态血压、脉压、心率及血压负荷相关.
目的 探討老老年人群動態血壓參數與動脈僵硬度的相關性.方法 篩選年齡≥80歲的老老年人238例,以血壓≥160/95 mm Hg(1 mm Hg=0.133 kPa)為標準,分為高血壓組(134例)和對照組(104例),併進行臂-踝脈搏傳導速度(baPWV)和24 h動態血壓鑑測.用Pearson分析動態血壓各參數與動脈僵硬度的相關性.結果 高血壓組baPWV高于對照組(P<0.05).高血壓組偶測收縮壓,24 h、晝間和夜間收縮壓,舒張壓、脈壓.收縮壓負荷及舒張壓負荷均高于對照組,夜間收縮壓下降率、舒張壓下降率低于對照組,差異有統計學意義(P<0.05,P<0.01).baPWV與偶測血壓;24 h收縮壓、舒張壓、脈壓;晝間收縮壓、舒張壓、脈壓、心率;夜間收縮壓、舒張壓、脈壓;收縮壓負荷、舒張壓負荷呈正相關(P<0.05,P<0.01),而與夜間收縮壓下降率呈負相關(P<0.01).結論 高血壓是老老年人群動脈僵硬度增加的一箇重要因素,動脈僵硬度與動態血壓、脈壓、心率及血壓負荷相關.
목적 탐토로노년인군동태혈압삼수여동맥강경도적상관성.방법 사선년령≥80세적로노년인238례,이혈압≥160/95 mm Hg(1 mm Hg=0.133 kPa)위표준,분위고혈압조(134례)화대조조(104례),병진행비-과맥박전도속도(baPWV)화24 h동태혈압감측.용Pearson분석동태혈압각삼수여동맥강경도적상관성.결과 고혈압조baPWV고우대조조(P<0.05).고혈압조우측수축압,24 h、주간화야간수축압,서장압、맥압.수축압부하급서장압부하균고우대조조,야간수축압하강솔、서장압하강솔저우대조조,차이유통계학의의(P<0.05,P<0.01).baPWV여우측혈압;24 h수축압、서장압、맥압;주간수축압、서장압、맥압、심솔;야간수축압、서장압、맥압;수축압부하、서장압부하정정상관(P<0.05,P<0.01),이여야간수축압하강솔정부상관(P<0.01).결론 고혈압시로노년인군동맥강경도증가적일개중요인소,동맥강경도여동태혈압、맥압、심솔급혈압부하상관.
Objective To investigate the relation between ambulatory blood pressure and arterial stiffness in the very elderly. Methods 238 very elderly (age≥80 years) were divided into two groups: 104 normotensive and 134 hypertensive (BP≥160/95 mm Hg, 1 mm Hg=0.133 kPa).Ambulatory blood pressure and brachial-ankle pulse wave velocity(baPWV) were monitored for all subjects. The relationship between parameters of ambulatory blood pressure and arterial stiff-ness was analyzed by Pearson correlation. Results The baPWV of the hypertensive group was significantly higher than that of normotensive group (P < 0.05,P < 0. 01). The casual systolic blood pressure(SBP), 24 h, day(D) and night(N) SBP, diastolic blood pressure(DBP), pulse pres-sure(PP),SBP load and DBP load in hypertensive group were significantly higher than those in the normotensive group. The rates of nocturnal SBP decrease and DBP decrease in the hyperten-sive group were significantly lower than those in the normotensives (P < 0.05, P < 0.01). Pear-son correlation analysis showed that baPWV was positively correlated with casual SBP,casual DBP, 24 h SBP, DBP, PP; day SBP, DBP, PP, HR; night SBP, DBP, PP, SBP load and DBP load,negatively correlated with night SBP decrease (P<0.01). Conclusion Present findings suggest that increase in arterial stiffness is an important factor of hypertension in the very elderly. Arterial stiffness is correlated with ambulatory SBP,DBP,PP, HR and BP load.
