中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2011年
2期
125-128
,共4页
近视%光学相干断层扫描仪%视网膜神经纤维层厚度
近視%光學相榦斷層掃描儀%視網膜神經纖維層厚度
근시%광학상간단층소묘의%시망막신경섬유층후도
Myopia%Tomography%Optical coherence tomography%RNFL thickness
目的 研究近视眼RNFL厚度的分布特征、相关影响因素和随相关因素的变化规律,为OCT在合并近视的青光眼诊断中的准确应用提供依据.方法 采用OCT测量90例近视患者单眼12个钟点位、4个象限的RNFL厚度和全周平均值等25个厚度参数并分别与屈光度、眼轴、眼压、年龄、性别和瞳孔大小进行相关性研究.结果 12个钟点位、4个象限的RNFL厚度分布特征:V4＜V5＜V10＜V3＜V6＜Vg＜V2＜V11＜V7＜V1＜V8＜V12(x2=611.172,P=0.000);N＜T＜I＜S(x2=156.264,P=0.000).随近视度数的加深和眼轴的延长,V1、V2、V3、V4、V6、V7、V12、Avg、S、I和N的RNFL厚度变薄;V9、V10、V11和T增厚.V1、V2、V12和S随年龄的增长而变薄.V2、V3、V4、Avg和N随眼压增高而变薄.结论 随着近视度数的加深和眼轴的延长,鼻侧RNFL逐渐变薄、颢侧RNFL逐渐增厚,鼻颞侧RNFL厚度差异逐渐明显.V1、V2、V3、V4、V6、V7、V12、Avg、S、I和N的RNFL厚度随眼轴长度及眼屈光度的增加而减少,在出现异常数值时,需考虑其眼轴及屈光度的影响,综合评价数值意义.青光眼也容易出现上方、下方和鼻侧RNFL厚度变薄,变薄区域与近视眼RNFL变薄区域有很大的交叉性.因此,可进一步通过直线回归方程,用患者的年龄、屈光度和眼轴长度对该异常区域的RNFL厚度进行校正,再与正常值进行比较.V5、V8、V9、V10、V11和T不随眼轴长度及眼屈光度的增加而减少,出现异常变薄时,无需考虑眼轴及屈光度的影响,应注意青光眼的可能性.V1、V2、V12和S随年龄的增大而变薄,在出现异常数值时,还需考虑年龄的影响.V2、V3、V4、Avg和N随眼压的增加而变薄,在青光眼的早期诊断中应重点关注.
目的 研究近視眼RNFL厚度的分佈特徵、相關影響因素和隨相關因素的變化規律,為OCT在閤併近視的青光眼診斷中的準確應用提供依據.方法 採用OCT測量90例近視患者單眼12箇鐘點位、4箇象限的RNFL厚度和全週平均值等25箇厚度參數併分彆與屈光度、眼軸、眼壓、年齡、性彆和瞳孔大小進行相關性研究.結果 12箇鐘點位、4箇象限的RNFL厚度分佈特徵:V4＜V5＜V10＜V3＜V6＜Vg＜V2＜V11＜V7＜V1＜V8＜V12(x2=611.172,P=0.000);N＜T＜I＜S(x2=156.264,P=0.000).隨近視度數的加深和眼軸的延長,V1、V2、V3、V4、V6、V7、V12、Avg、S、I和N的RNFL厚度變薄;V9、V10、V11和T增厚.V1、V2、V12和S隨年齡的增長而變薄.V2、V3、V4、Avg和N隨眼壓增高而變薄.結論 隨著近視度數的加深和眼軸的延長,鼻側RNFL逐漸變薄、顥側RNFL逐漸增厚,鼻顳側RNFL厚度差異逐漸明顯.V1、V2、V3、V4、V6、V7、V12、Avg、S、I和N的RNFL厚度隨眼軸長度及眼屈光度的增加而減少,在齣現異常數值時,需攷慮其眼軸及屈光度的影響,綜閤評價數值意義.青光眼也容易齣現上方、下方和鼻側RNFL厚度變薄,變薄區域與近視眼RNFL變薄區域有很大的交扠性.因此,可進一步通過直線迴歸方程,用患者的年齡、屈光度和眼軸長度對該異常區域的RNFL厚度進行校正,再與正常值進行比較.V5、V8、V9、V10、V11和T不隨眼軸長度及眼屈光度的增加而減少,齣現異常變薄時,無需攷慮眼軸及屈光度的影響,應註意青光眼的可能性.V1、V2、V12和S隨年齡的增大而變薄,在齣現異常數值時,還需攷慮年齡的影響.V2、V3、V4、Avg和N隨眼壓的增加而變薄,在青光眼的早期診斷中應重點關註.
목적 연구근시안RNFL후도적분포특정、상관영향인소화수상관인소적변화규률,위OCT재합병근시적청광안진단중적준학응용제공의거.방법 채용OCT측량90례근시환자단안12개종점위、4개상한적RNFL후도화전주평균치등25개후도삼수병분별여굴광도、안축、안압、년령、성별화동공대소진행상관성연구.결과 12개종점위、4개상한적RNFL후도분포특정:V4＜V5＜V10＜V3＜V6＜Vg＜V2＜V11＜V7＜V1＜V8＜V12(x2=611.172,P=0.000);N＜T＜I＜S(x2=156.264,P=0.000).수근시도수적가심화안축적연장,V1、V2、V3、V4、V6、V7、V12、Avg、S、I화N적RNFL후도변박;V9、V10、V11화T증후.V1、V2、V12화S수년령적증장이변박.V2、V3、V4、Avg화N수안압증고이변박.결론 수착근시도수적가심화안축적연장,비측RNFL축점변박、호측RNFL축점증후,비섭측RNFL후도차이축점명현.V1、V2、V3、V4、V6、V7、V12、Avg、S、I화N적RNFL후도수안축장도급안굴광도적증가이감소,재출현이상수치시,수고필기안축급굴광도적영향,종합평개수치의의.청광안야용역출현상방、하방화비측RNFL후도변박,변박구역여근시안RNFL변박구역유흔대적교차성.인차,가진일보통과직선회귀방정,용환자적년령、굴광도화안축장도대해이상구역적RNFL후도진행교정,재여정상치진행비교.V5、V8、V9、V10、V11화T불수안축장도급안굴광도적증가이감소,출현이상변박시,무수고필안축급굴광도적영향,응주의청광안적가능성.V1、V2、V12화S수년령적증대이변박,재출현이상수치시,환수고필년령적영향.V2、V3、V4、Avg화N수안압적증가이변박,재청광안적조기진단중응중점관주.
Objective To research the characteristics,related factors and changing regularity of RNFL thickness in myopia and to provide accurate diagnosis basis in glaucoma with myopia by measurement of RNFL thickness using OCT.Methods Ninety patients with myopia(90 eyes)were included.The RNFL thickness in different sections was measured by OCT.The difference among the RNFL thickness in different sections and the relation among the RNFL thickness in different sections,diopter,axial length,intraocular pressure,age,gender and pupil diameter were analyzed.Results OCT assessment revealed a significant difference of the RNFL thickness in different sections:V4 ＜ V5 ＜V10 ＜V3 ＜ V6 ＜ V9 ＜ V2 ＜ Vu ＜ V7 ＜ V1 ＜V8 ＜ V12(x2 = 611.172,P=0.000); N＜T＜I＜S(x2= 156.264,P=0.000).With the increase of diopter and axial length,the RNFL thickness ofV1,V2,V3,V4,V6,V7,V12,Avg,S,I and N was decreased,while V9,V10,V11 and T was increased.V1,V2,V12 and S were decreased while age increased.V2,V3,V4,Avg and N were decreased while intraocular pressure increased.Conclusions With the increase of diopter and axial length,the RNFL thickness of N decreased while T increased,so the difference between two quadrants become more and more significant.When the RNFL thickness of V1,V2,V3,V4,V6,V7,V12,Avg,S,I and N become thinner,the affection of diopter and axial length in myopia should be considered.The same change of S,I and N often occur in glaucoma too,so we should use age,diopter and axial length to correct RNFL thickness of these sections by regression equation firstly,and then compare with normal.The RNFL thickness of V5,V8,V9,V10,V11 and T is not decreased with the increase of diopter and axial length,so the decrease of these sections implies the possibility of glaucoma.The change of V1,V2,V12 and S with age is also important.V2,V3,V4,Avg and N are related with intraocular pressure and should be attached great inportance to in early diagnosis in glaucoma.
