国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2011年
24期
3054-3056
,共3页
梅尼埃病%甲状腺机能减退症%病例对照%眩晕
梅尼埃病%甲狀腺機能減退癥%病例對照%眩暈
매니애병%갑상선궤능감퇴증%병례대조%현훈
Meniere's disease%Hypothyroidism%Case-control study%Dizziness
目的 评估梅尼埃病患者合并甲状腺机能减退症的免疫相关性.方法 回顾性病例对照研究,比较梅尼埃病(MD)与普通眩晕症之间同期应用甲状腺素补充替代疗法患者的分布情况.2005年2月-2010年5月间收治的以眩晕为主诉的患者1908例,其中50例梅尼埃病患者,符合1996年10月中华医学会耳鼻咽喉科学会全国会议(上海)制定的梅尼埃病诊断依据.对照组50例眩晕症患者,年龄、性别配比对照.结果 50例梅尼埃病患者中16例(32％)同期服用甲状腺素治疗甲状腺机能减退症,对照组2例(4％)应用甲状腺素补充替代疗法.xz检验两组差异有极显著性(P＜ 0.001).梅尼埃病患者中位年龄为56岁,小于56岁的26例中有5例(19％)服用甲状腺素,56岁以上(包括56岁)的24例中有11例(46％)服用甲状腺素(P＜0.05).听力损失严重程度以及单耳或双耳听力损失与MD患者是否伴有甲状腺功能障碍差异无显著性.结论 梅尼埃病.与特发性甲状腺机能低下症有关,发现甲状腺机能减退症最大的几率是在56岁以上的MD患者中.
目的 評估梅尼埃病患者閤併甲狀腺機能減退癥的免疫相關性.方法 迴顧性病例對照研究,比較梅尼埃病(MD)與普通眩暈癥之間同期應用甲狀腺素補充替代療法患者的分佈情況.2005年2月-2010年5月間收治的以眩暈為主訴的患者1908例,其中50例梅尼埃病患者,符閤1996年10月中華醫學會耳鼻嚥喉科學會全國會議(上海)製定的梅尼埃病診斷依據.對照組50例眩暈癥患者,年齡、性彆配比對照.結果 50例梅尼埃病患者中16例(32％)同期服用甲狀腺素治療甲狀腺機能減退癥,對照組2例(4％)應用甲狀腺素補充替代療法.xz檢驗兩組差異有極顯著性(P＜ 0.001).梅尼埃病患者中位年齡為56歲,小于56歲的26例中有5例(19％)服用甲狀腺素,56歲以上(包括56歲)的24例中有11例(46％)服用甲狀腺素(P＜0.05).聽力損失嚴重程度以及單耳或雙耳聽力損失與MD患者是否伴有甲狀腺功能障礙差異無顯著性.結論 梅尼埃病.與特髮性甲狀腺機能低下癥有關,髮現甲狀腺機能減退癥最大的幾率是在56歲以上的MD患者中.
목적 평고매니애병환자합병갑상선궤능감퇴증적면역상관성.방법 회고성병례대조연구,비교매니애병(MD)여보통현훈증지간동기응용갑상선소보충체대요법환자적분포정황.2005년2월-2010년5월간수치적이현훈위주소적환자1908례,기중50례매니애병환자,부합1996년10월중화의학회이비인후과학회전국회의(상해)제정적매니애병진단의거.대조조50례현훈증환자,년령、성별배비대조.결과 50례매니애병환자중16례(32％)동기복용갑상선소치료갑상선궤능감퇴증,대조조2례(4％)응용갑상선소보충체대요법.xz검험량조차이유겁현저성(P＜ 0.001).매니애병환자중위년령위56세,소우56세적26례중유5례(19％)복용갑상선소,56세이상(포괄56세)적24례중유11례(46％)복용갑상선소(P＜0.05).은력손실엄중정도이급단이혹쌍이은력손실여MD환자시부반유갑상선공능장애차이무현저성.결론 매니애병.여특발성갑상선궤능저하증유관,발현갑상선궤능감퇴증최대적궤솔시재56세이상적MD환자중.
Objective To estimate the prevalence of hypothyroidism in a population of patients with Meniere's disease(MD).Methods Retrospective case-control study was carried out to compare the use of thyroid hormone supplements between patients with MD and controls with only dizziness.The 50 patients who met the criteria for MD were identified from a database of 1908 patients with dizziness within over a 5-year period.Results Among the 50 cases,16(32％)were taking thyroid hormone supplements in contrast to 2(4％) matching significant difference(P＜ 0.001).The median age of the patients with MD was 56 years old,and 5(1 9％)of the 26patients younger than 56 years old were taking thyroid hormone supplements,comparing with 11(46％)of 24patients who were 56 years old or older (P＜ 0.05).There were no statistical significant differences in the severity of hearing loss,pattern of hearing loss,or prevalence of bilateral of hearing loss,between patients with MD who were taking thyroid hormone supplements and patients without MD.Conclusion Meniere's disease is associated with idiopathic hypothyroidism.The likelihood of finding hypothyroidism is highest in MD patients older than 56 years.
