CAJ | 학술논문

目的评价急性心肌梗死并发窒间隔穿孔封堵治疗的疗效.方法 12例临床经心电图、心肌坏死标记物及心脏超声确诊为急性心肌梗死并发室间隔穿孔的患者,经药物治疗调整心功能后实施介入治疗封堵术,其中2例患者择期实行冠状动脉造影球囊扩张(PTCA)及支架置入术.结果 (1)全部12例患者,缺损累及膜周部2例,肌部10例(其中心尖部3例);12例患者,9例封堵成功,9例患者存活;相关的并发症封堵器脱落2例和恶性心律失常(心室颤动)1例.(2)室间隔穿孔发生到行封堵术的时间间隔为(15.5±9.2)d,9例存活患者术后至出院天数为(11.3±5.2)d.(3)2例患者同时均经冠状动脉造影成功地于严重狄窄处共置入支架4枚.结论采用导管法封堵急性心肌梗死并发室间隔穿孔能在一定的程度上降低病死率,但技术有待于进一步完善和发展.
목적 평개급성심기경사병발질간격천공봉도치료적료효.방법 12례림상경심전도、심기배사표기물급심장초성학진위급성심기경사병발실간격천공적환자,경약물치료조정심공능후실시개입치료봉도술,기중2례환자택기실행관상동맥조영구낭확장(PTCA)급지가치입술.결과 (1)전부12례환자,결손루급막주부2례,기부10례(기중심첨부3례);12례환자,9례봉도성공,9례환자존활;상관적병발증봉도기탈락2례화악성심률실상(심실전동)1례.(2)실간격천공발생도행봉도술적시간간격위(15.5±9.2)d,9례존활환자술후지출원천수위(11.3±5.2)d.(3)2례환자동시균경관상동맥조영성공지우엄중적착처공치입지가4매.결론 채용도관법봉도급성심기경사병발실간격천공능재일정적정도상강저병사솔,단기술유대우진일보완선화발전.
Objective To evaluate the therapeutic effect of transcather closure in patients with postinfarction ventricular septal defects (VSD). Methods Transcatheter VSD closure was performed in 12 patients with postinfarction VSD (10 muscular and 2 membranes defects) on top of standard pharmacotherapy and percutaneous transluminal coronary angioplasty (PTCA) as indicated. Results (1) Percutaneous interventional VSD closure was suceessful in 9 out 12 patients (75%) and these 9 patients survived post procedure. (2)The medial time between VSD occurrence and closure was (15.5±9.2) days. Procedure-related complications such as device embolization and malignant arrhythmia occurred in 3 patients (25%). The medial time between procedure and discharge from hospital was (11.3±5.2) days. (3) Coronary angiography was performed in 2 patients and 4 stents were implanted in diseased lesions. Conclusion Transeatheter closure could be successfully performed in selected patients with postinfarction VSD.