中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2010年
10期
4-6
,共3页
肺疾病,慢性阻塞性%呼吸功能不全%危险因素
肺疾病,慢性阻塞性%呼吸功能不全%危險因素
폐질병,만성조새성%호흡공능불전%위험인소
Pulmonary disease,chronic obstructive%Respiratory insufficiency%Risk factors
目的 探讨慢性阻塞性肺疾病(COPD)并发呼吸衰竭相关危险因素和预后因素.方法 对2005年3月至2008年2月收治的110例COPD患者的临床资料进行回顾性分析,根据是否发生呼吸衰竭分为呼吸衰竭组(40例)和非呼吸衰竭组(70例).结果 呼吸衰竭组每年急性发作次数、尿酸、总蛋白、白蛋白、体重指数与非呼吸衰竭组比较差异有统计学意义[分别为(5.54±1.16)次/年比(2.75±0.78)次,年、(283.75±72.49)mmol/L比(359.87±41.50)mmol/L、(58.77±1.54)g/L比(63.95±2.04)g/L、(36.15±1.08)g/L比(36.96±1.48)g/L、(20.33±0.99)kg/m2比(21.16±1.36)kg/m2](P<0.01);COPD分度、院内感染、酸碱平衡紊乱两组比较差异有统计学意义(P<0.05或<0.01).呼吸衰竭死亡患者和好转患者动脉血氧分压比较差异无统计学意义(P>0.05),pH值、动脉血二氧化碳分压、血钠、血氯比较差异有统计学意义(P<0.01).结论 COPD并发呼吸衰竭相关危险因素多.
目的 探討慢性阻塞性肺疾病(COPD)併髮呼吸衰竭相關危險因素和預後因素.方法 對2005年3月至2008年2月收治的110例COPD患者的臨床資料進行迴顧性分析,根據是否髮生呼吸衰竭分為呼吸衰竭組(40例)和非呼吸衰竭組(70例).結果 呼吸衰竭組每年急性髮作次數、尿痠、總蛋白、白蛋白、體重指數與非呼吸衰竭組比較差異有統計學意義[分彆為(5.54±1.16)次/年比(2.75±0.78)次,年、(283.75±72.49)mmol/L比(359.87±41.50)mmol/L、(58.77±1.54)g/L比(63.95±2.04)g/L、(36.15±1.08)g/L比(36.96±1.48)g/L、(20.33±0.99)kg/m2比(21.16±1.36)kg/m2](P<0.01);COPD分度、院內感染、痠堿平衡紊亂兩組比較差異有統計學意義(P<0.05或<0.01).呼吸衰竭死亡患者和好轉患者動脈血氧分壓比較差異無統計學意義(P>0.05),pH值、動脈血二氧化碳分壓、血鈉、血氯比較差異有統計學意義(P<0.01).結論 COPD併髮呼吸衰竭相關危險因素多.
목적 탐토만성조새성폐질병(COPD)병발호흡쇠갈상관위험인소화예후인소.방법 대2005년3월지2008년2월수치적110례COPD환자적림상자료진행회고성분석,근거시부발생호흡쇠갈분위호흡쇠갈조(40례)화비호흡쇠갈조(70례).결과 호흡쇠갈조매년급성발작차수、뇨산、총단백、백단백、체중지수여비호흡쇠갈조비교차이유통계학의의[분별위(5.54±1.16)차/년비(2.75±0.78)차,년、(283.75±72.49)mmol/L비(359.87±41.50)mmol/L、(58.77±1.54)g/L비(63.95±2.04)g/L、(36.15±1.08)g/L비(36.96±1.48)g/L、(20.33±0.99)kg/m2비(21.16±1.36)kg/m2](P<0.01);COPD분도、원내감염、산감평형문란량조비교차이유통계학의의(P<0.05혹<0.01).호흡쇠갈사망환자화호전환자동맥혈양분압비교차이무통계학의의(P>0.05),pH치、동맥혈이양화탄분압、혈납、혈록비교차이유통계학의의(P<0.01).결론 COPD병발호흡쇠갈상관위험인소다.
Objective To discuss relative risk factors and prognosis factors of chronic obstructive pulmonary disease (COPD) combined with respiratory failure.Methods Retrospective investigation was carried out to analyze the clinical data of 110 patients with COPD from March 2005 to February 2008.These patients were divided into two groups according to the condition of respiratory failure,respiratory failure group(40 cases) and non-respiratory failure group(70 cases).Results There were significant differences in the frequency of exacerbation,uric acid,total protein,albumin,bady-mass index between two groups [(5.54 ± 1.16) times/year vs (2.75 ±0.78) times/year,(283.75 ±72.49) mmol/L vs (359.87 ±41.50)mmol/L,(58.77 ± 1.54) g/Lvs(63.95 ±2.04) g/L,(36.15 ± 1.08) g/L vs(36.96 ± 1.48) g/L,(20.33 ±0.99)kg/m2 vs (21.16 ± 1.36) kg/m2](P < 0.01).There were significant differences in COPD stage,nosocomial infection,acid-base disturbance between two groups(P< 0.05 or < 0.01).There was no statistical significance of partial pressure of oxygen in artery between the respiratory failure survival patients and dead patients (P >0.05).There were statistical significances in pH,partial pressure of carbon dioxide in artery,blood Na+,blood Cl-between the respiratory failure survival patients and dead patients (P< 0.01).Conclusion There are many relative risk factors of COPD combined with respiratory failure.
