CAJ | 학술논문

目的了解河南商城地区可能存在的蜱媒传染病的感染情况.方法通过现场调查和实验室检测相结合的方法,对该地区病例、媒介蜱和宿主动物进行了调查.对43例病例的临床表现和实验室检测进行回顾性分析.用PCR和序列测定方法对媒介蜱和啮齿类宿主动物样本中查菲埃立克体、无形体、Q热立克次体的感染进行检测.结果病例临床表现以发热伴白细胞、血小板减少和多脏器功能损害为主.3只全沟硬蜱PCR扩增阳性,其中1只同时感染嗜吞噬细胞无形体和Q热立克次体,2只单独感染嗜吞噬细胞无形体.宿主动物样本中有2只为无形体感染.结论河南商城地区存在无形体、Q热立克次体的感染,应引起公共卫生部门的高度重视.
목적 료해하남상성지구가능존재적비매전염병적감염정황.방법 통과현장조사화실험실검측상결합적방법,대해지구병례、매개비화숙주동물진행료조사.대43례병례적림상표현화실험실검측진행회고성분석.용PCR화서렬측정방법대매개비화교치류숙주동물양본중사비애립극체、무형체、Q열립극차체적감염진행검측.결과 병례림상표현이발열반백세포、혈소판감소화다장기공능손해위주.3지전구경비PCR확증양성,기중1지동시감염기탄서세포무형체화Q열립극차체,2지단독감염기탄서세포무형체.숙주동물양본중유2지위무형체감염.결론 하남상성지구존재무형체、Q열립극차체적감염,응인기공공위생부문적고도중시.
Objective To study the existence of tick-borne disease in Shangchen, Henan. Methods Epidemiologic, clinical data were collected by interviewing patients and retrieving medical records. Using polymerase chain reaction assays (PCR) and sequence analysis, Ehrlichia chaffeensis, Anaplasma, Coxiella burnetii were detected in ticks and rodents samples. Results Most patients had a moderately severe febrile illness with thrombocytopenia, leukopnia and organ failure. One Ixodes persulcatus was coinfection with Anaplasma phagocytophilum and Coxiella burnetii, while two Ixodes persulcatus were infection with Anaplasma phagocytophilum. Two rodents samples were positive with Anaplasma . Conclusions Anaplasma phagocytophilum and Coxiella bumetii exist in Shangcheng. Local public health authorities should pay much attention to these pathogens.