CAJ | 학술논문

目的从豆科葛属植物云南葛藤Pueraria peduncularis中分离得到10个化合物.方法通过波谱和化学方法分别进行鉴定.结果它们的化学结构为:3-O-[β-D-吡喃葡萄糖(1→3)-β-D-吡喃葡萄糖醛酸甲酯苷]-3β,15a,23-三羟基齐墩果-12-烯-16-酮(Ⅰ),大豆素(Ⅱ),染料木素(Ⅲ),大豆苷(Ⅳ),染料木苷(V),3β,15a-二羟基齐墩果-12-烯-16-酮(Ⅵ),羽扇醇(Ⅶ),桦木酸(Ⅶ),α-菠甾醇葡萄糖苷(Ⅸ)和α-菠甾醇(X).结论化合物Ⅰ对黑曲霉具有抑制活性.
목적종두과갈속식물운남갈등Pueraria peduncularis중분리득도10개화합물.방법통과파보화화학방법분별진행감정.결과타문적화학결구위:3-O-[β-D-필남포도당(1→3)-β-D-필남포도당철산갑지감]-3β,15a,23-삼간기제돈과-12-희-16-동(Ⅰ),대두소(Ⅱ),염료목소(Ⅲ),대두감(Ⅳ),염료목감(V),3β,15a-이간기제돈과-12-희-16-동(Ⅵ),우선순(Ⅶ),화목산(Ⅶ),α-파치순포도당감(Ⅸ)화α-파치순(X).결론화합물Ⅰ대흑곡매구유억제활성.
Object To investigate the chemical constituents from the stem of Pueraria peduncularis (Grah. ex Benth. ) Benth. Methods The constituents were isolated on silica gel column chromatography.Their structures were elucidated by chemical and spectroscopic evidence. Results Ten compounds were comfirmed as 3-O- [β-D-glucopyranosyl- ( 1 → 3 )-β-D- 6-O-methyl-glucuronopyranosyl ]- 3β3, 1 Sa, 2 3-trihydroxy-olean-12-en-16-one (Ⅰ), daidzein (Ⅱ), genistein ( Ⅲ ), daidzin ( Ⅳ ), genistin ( V ), 3β3, 15α-dihydroxy-olean-12-en-16-one (VⅥ), lupeol (Ⅶ), betulinic acid (Ⅷ), α-spinasterol-glucopyranoside (ⅨX)and α-spinasterol ( X ). Conclusion Compound I exhibited antimicrobial activity against Aspergillus niger.Compounds Ⅱ～ X were first isolated from this plant.