中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2012年
5期
540-543
,共4页
弱视%明视负波%视网膜神经节细胞
弱視%明視負波%視網膜神經節細胞
약시%명시부파%시망막신경절세포
Amblyopia%PhNR (Photopic Negative Response)%Retinal ganglion cells
目的 通过对正常人与弱视患者视网膜电图明视负波(PhNR)对比分析,探讨PhNR在弱视患者中的临床应用价值.方法 正常人30名60只眼(年龄5～35岁),弱视48例60只眼(5～35岁),选择蓝色背景光(亮度为25 cd/m2),刺激光为红色光(亮度2 cds/m2)下进行明视负波检查,再根据视觉发育敏感期分为＜12岁和≥12岁两个年龄组,记录各种检查结果并分析.结果 (1)弱视组PhNR反应振幅均值均较正常组降低,其差异有统计学意义.(2)弱视组PhNR潜伏期和正常组相 似,其差异不具有统计学意义.(3)正常人≥12岁年龄组PhNR反应振幅均值较＜12岁年龄组降低,潜伏期延迟,其差异具有统计学意义.结论 (1)弱视患者PhNR反应振幅降低,与正常组差异显著有统计学意义,提示PhNR可以作为弱视患者的一个视功能评价指标,弱视患者视网膜神经节细胞功能存在一定程度的抑制.(2)≥12岁PhNR的反应振幅较＜12岁降低,潜伏期延迟,提示PhNR反应与年龄有关联.
目的 通過對正常人與弱視患者視網膜電圖明視負波(PhNR)對比分析,探討PhNR在弱視患者中的臨床應用價值.方法 正常人30名60隻眼(年齡5～35歲),弱視48例60隻眼(5～35歲),選擇藍色揹景光(亮度為25 cd/m2),刺激光為紅色光(亮度2 cds/m2)下進行明視負波檢查,再根據視覺髮育敏感期分為＜12歲和≥12歲兩箇年齡組,記錄各種檢查結果併分析.結果 (1)弱視組PhNR反應振幅均值均較正常組降低,其差異有統計學意義.(2)弱視組PhNR潛伏期和正常組相 似,其差異不具有統計學意義.(3)正常人≥12歲年齡組PhNR反應振幅均值較＜12歲年齡組降低,潛伏期延遲,其差異具有統計學意義.結論 (1)弱視患者PhNR反應振幅降低,與正常組差異顯著有統計學意義,提示PhNR可以作為弱視患者的一箇視功能評價指標,弱視患者視網膜神經節細胞功能存在一定程度的抑製.(2)≥12歲PhNR的反應振幅較＜12歲降低,潛伏期延遲,提示PhNR反應與年齡有關聯.
목적 통과대정상인여약시환자시망막전도명시부파(PhNR)대비분석,탐토PhNR재약시환자중적림상응용개치.방법 정상인30명60지안(년령5～35세),약시48례60지안(5～35세),선택람색배경광(량도위25 cd/m2),자격광위홍색광(량도2 cds/m2)하진행명시부파검사,재근거시각발육민감기분위＜12세화≥12세량개년령조,기록각충검사결과병분석.결과 (1)약시조PhNR반응진폭균치균교정상조강저,기차이유통계학의의.(2)약시조PhNR잠복기화정상조상 사,기차이불구유통계학의의.(3)정상인≥12세년령조PhNR반응진폭균치교＜12세년령조강저,잠복기연지,기차이구유통계학의의.결론 (1)약시환자PhNR반응진폭강저,여정상조차이현저유통계학의의,제시PhNR가이작위약시환자적일개시공능평개지표,약시환자시망막신경절세포공능존재일정정도적억제.(2)≥12세PhNR적반응진폭교＜12세강저,잠복기연지,제시PhNR반응여년령유관련.
Objective To analyze the clinical application value of Photopic Negative Response (PhNR) in amblyopia. Methods PhNR was recorded and analyzed from 60 normal eyes and 60 amblyopia eyes by using red flashes on a blue background. Results Amplitudes of PhNR in amblyopia were lower than those of the normal group,there were statistically significant differences between them.Latencies of PhNR in amblyopia were similar to normal group,there were no statistically significant differences between them.In normal group,amplitudes of PhNR of ≥12 year older age group were lower and latencies were longer compared with ＜12 years low group,there was statistically significant difference. Conclusions Amplitudes of PhNR in amblyopia are lower than those of the normal group,and the function of retinal ganglion cells of amblyopia is damaged.Amplitudes of PhNR decrease with age,latencies of PhNR delay with age,these suggest that PhNR is significantly associated with age.
