心血管病学进展
心血管病學進展
심혈관병학진전
ADVANCES IN CARDIOVASCULAR DISEASES
2009年
6期
988-991
,共4页
氯吡格雷抵抗%血小板P2Y_(12)受体
氯吡格雷牴抗%血小闆P2Y_(12)受體
록필격뢰저항%혈소판P2Y_(12)수체
clopidogrel resistance%platelet P2Y_(12) receptor
目前,关于血小板对氯吡格雷抵抗这一现象发生机制的解释,正日益成为关注的热点,除与患者的低依从性、剂量不足、吸收不良、血小板代谢等多种因素有关外,还与血小板P2Y_(12)受体的功能状态有着密切关系.
目前,關于血小闆對氯吡格雷牴抗這一現象髮生機製的解釋,正日益成為關註的熱點,除與患者的低依從性、劑量不足、吸收不良、血小闆代謝等多種因素有關外,還與血小闆P2Y_(12)受體的功能狀態有著密切關繫.
목전,관우혈소판대록필격뢰저항저일현상발생궤제적해석,정일익성위관주적열점,제여환자적저의종성、제량불족、흡수불량、혈소판대사등다충인소유관외,환여혈소판P2Y_(12)수체적공능상태유착밀절관계.
At present, increasing attention has been given to the explanation for the phenomenon of clopidogrel resistance. The functional status of the platelet P2Y_(12) receptor has a close relationship to the occurrence of clopidogrel resistance in addition to other various factors such as noncompliance, under dosing, poor absorption, and accelerated platelet turnover.