国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2012年
13期
1902-1904
,共3页
无创正压通气%呼吸衰竭%COPD%疗效
無創正壓通氣%呼吸衰竭%COPD%療效
무창정압통기%호흡쇠갈%COPD%료효
Noninvasive positive pressure ventilation%Respiratory failure%Chronic obstructive pulmonary disease%Efficacy
目的 探讨无创正压呼吸机辅助通气( BiPAP)治疗慢性阻塞性肺病(COPD)合并呼吸衰竭的临床疗效.方法 选取2009年1月至2012年2月我院收治的68例COPD合并呼吸衰竭患者,将其随机分为治疗组(34例)和对照组(34例),对照组给予抗感染、止咳、化痰、平喘、解痉等常规治疗,治疗组在此基础上加用BiPAP呼吸机辅助通气治疗.观察并比较两组患者治疗前、后呼吸频率、心率、气血指标及病情改善情况.结果 治疗72 h后,治疗组患者呼吸频率及心率显著优于对照组[(20±3)次/min vs.( 26±3)次/min,(91±11)次/min vs.( 109±12)次/min,P＜0.05],pH、Pa02、FV1、FV1/FVC显著高于对照组(P＜0.05),PaC02显著低于对照组(P＜0.05),而对照组各指标治疗后与治疗前比较差异无统计学意义(P＞0.05).治疗期间均无严重不良反应发生.结论 无创正压呼吸机辅助通气治疗COPD合并呼吸衰竭的临床疗效确切,可明显缓解患者呼吸困难,改善动脉血气及肺功能,值得临床推广应用.
目的 探討無創正壓呼吸機輔助通氣( BiPAP)治療慢性阻塞性肺病(COPD)閤併呼吸衰竭的臨床療效.方法 選取2009年1月至2012年2月我院收治的68例COPD閤併呼吸衰竭患者,將其隨機分為治療組(34例)和對照組(34例),對照組給予抗感染、止咳、化痰、平喘、解痙等常規治療,治療組在此基礎上加用BiPAP呼吸機輔助通氣治療.觀察併比較兩組患者治療前、後呼吸頻率、心率、氣血指標及病情改善情況.結果 治療72 h後,治療組患者呼吸頻率及心率顯著優于對照組[(20±3)次/min vs.( 26±3)次/min,(91±11)次/min vs.( 109±12)次/min,P＜0.05],pH、Pa02、FV1、FV1/FVC顯著高于對照組(P＜0.05),PaC02顯著低于對照組(P＜0.05),而對照組各指標治療後與治療前比較差異無統計學意義(P＞0.05).治療期間均無嚴重不良反應髮生.結論 無創正壓呼吸機輔助通氣治療COPD閤併呼吸衰竭的臨床療效確切,可明顯緩解患者呼吸睏難,改善動脈血氣及肺功能,值得臨床推廣應用.
목적 탐토무창정압호흡궤보조통기( BiPAP)치료만성조새성폐병(COPD)합병호흡쇠갈적림상료효.방법 선취2009년1월지2012년2월아원수치적68례COPD합병호흡쇠갈환자,장기수궤분위치료조(34례)화대조조(34례),대조조급여항감염、지해、화담、평천、해경등상규치료,치료조재차기출상가용BiPAP호흡궤보조통기치료.관찰병비교량조환자치료전、후호흡빈솔、심솔、기혈지표급병정개선정황.결과 치료72 h후,치료조환자호흡빈솔급심솔현저우우대조조[(20±3)차/min vs.( 26±3)차/min,(91±11)차/min vs.( 109±12)차/min,P＜0.05],pH、Pa02、FV1、FV1/FVC현저고우대조조(P＜0.05),PaC02현저저우대조조(P＜0.05),이대조조각지표치료후여치료전비교차이무통계학의의(P＞0.05).치료기간균무엄중불량반응발생.결론 무창정압호흡궤보조통기치료COPD합병호흡쇠갈적림상료효학절,가명현완해환자호흡곤난,개선동맥혈기급폐공능,치득림상추엄응용.
Objective To explore the clinical efficacy of noninvasive positive pressure ventilation in the treatment of chronic obstructive pnlmonary disease ( COPD )with respiratory failure.Methods 68 patients with COPD and respiratory faohre who had been treated from January 2009 to February 2012 in our hospital were randomly divided into study group( 34 patients )and control group( 34 patients ).The control group received conventional therapies for infection control and symptomatic treatment; while the study group received mechanical ventilation with BiPAP on the basis of routine therapies.Respiratory rate,heart rate,and arterial blood gas were observed and compared between the two groups.Results 72h after treatment,the respiratory rate and heart rate were significantly better in the study group than in the control group ( P＜ 0.05 ); pH,PaO2,FV 1,and FV 1/FVC were significantly higher in the study group ( P＜ 0.05 ),whereas PaCO2 was significantly lower( P＜ 0.05 ),while no significant changes occurred in the control group as compared with the baselines ( P ＞ 0.05 ).No severe adverse reactions occurred during treatment.Conclusions Noninvasive positive pressure ventilation is effective in the treatment of COPD with respiratory failure.It can significantly relieve dyspnea and obviously improve arterial blood gas and lung function.It is worth popularizing clinically.
