CAJ | 학술논문

目的调查贵阳城区成人维生素D营养状况.方法用整群抽样的方法抽取贵阳市云岩区宅吉社区中20～79岁(年龄中位数为45.2岁)健康成人1 500名,于2009年11月至2010年2月进行问卷调查,并采集清晨空腹静脉血分离血清,用美国DiaSorin公司的放射免疫试剂盒测定血清25-羟维生素D[25(OH)D]水平.结果贵阳城区成人血清25(OH)D平均水平为(20.4±9.0)ng/ml;成人25(OH)D缺乏[25(OH)D＜20ng/ml]、不足[20ng/ml≤25(OH)D＜30 ng/ml]、正常[25(OH)D≥30 ng/m1]分别为52.3%、32.3%及15.4%.贵阳城区青年、中年、老年人群血清25(OH)D平均水平依次为(18.2±9.2)、(22.8±8.7)及(19.9±7.8)ng/ml.青年、中年与老年人群维生素D缺乏依次为62.8%、40.2%与55.4%.高学历人群(≥13年)维生素D缺乏为61.6%,低体重人群(体重指数＜18.5 kg/m2)维生素D缺乏为64.4%.结论贵阳城区成人维生素D缺乏普遍,尤其见于老年人及青年人群,并受文化程度、年龄、吸烟等因素影响.
목적 조사귀양성구성인유생소D영양상황.방법 용정군추양적방법추취귀양시운암구 택길사구중20～79세(년령중위수위45.2세)건강성인1 500명,우2009년11월지2010년2월진행문권조사,병채집청신공복정맥혈분리혈청,용미국DiaSorin공사적방사면역시제합측정혈청25-간유생소D[25(OH)D]수평.결과 귀양성구성인혈청25(OH)D평균수평위(20.4±9.0)ng/ml;성인25(OH)D결핍[25(OH)D＜20ng/ml]、불족[20ng/ml≤25(OH)D＜30 ng/ml]、정상[25(OH)D≥30 ng/m1]분별위52.3%、32.3%급15.4%.귀양성구청년、중년、노년인군혈청25(OH)D평균수평의차위(18.2±9.2)、(22.8±8.7)급(19.9±7.8)ng/ml.청년、중년여노년인군유생소D결핍의차위62.8%、40.2%여55.4%.고학력인군(≥13년)유생소D결핍위61.6%,저체중인군(체중지수＜18.5 kg/m2)유생소D결핍위64.4%.결론 귀양성구성인유생소D결핍보편,우기견우노년인급청년인군,병수문화정도、년령、흡연등인소영향.
Objective To evaluate vitamin D status in healthy adults living in Guiyang. Method 1 500 healthy volunteers aged 20-79 years ( mean 45.2 years ) were recruited from a community in Guiyang by cluster sampling method. Questionnaires for living habits and fasting blood samples were collected from November, 2009 to February, 2010. Serum 25 ( OH ) D concentrations were measured by radioimmunoassay, using the DiaSorin kit,USA. Results The average serum 25 ( OH ) D level was ( 20. 4±9.0 ) ng/ml. The percentages of vitamin D deficiency [25 ( OH ) D ＜ 20 ng/ml], insufficiency [20 ng/ml ≤ 25 ( OH ) D ＜ 30 ng/ml], and sufficiency [25 ( OH ) D ≥ 30ng/ml] were 52. 3% , 32. 3% , and 15.4% , respectively. The 25 (OH) D concentrations in the young, middle-aged,and elderly were ( 18. 2±9. 2), (22. 8±8. 7), and ( 19. 9±7.8) ng/ml, respectively. The percentages of vitamin D deficiency in these groups were 62. 8%, 40. 2%, and 55.4%, being 61.6% in higher educational group ( ≥ 13 years) and 64. 4% in the group with lower body mass index ( ＜ 18.5 kg/m2 ). Conclusion Vitamin D deficiency is common in Guiyang including all age groups, especially among the youth and the elderly. Serum 25-hydroxyvitamin D level is also influenced by education, age, smoking, and other factors.