CAJ | 학술논문

目的探讨脑肿瘤弥散张量成像(DTI)的特点及其在脑肿瘤中的诊断和鉴别诊断价值.方法对39例经病理证实的脑肿瘤患者(脑膜瘤10例,胶质瘤17例,转移瘤12例),采用PhilipsAchieva 1.5 T磁共振行常规MRI和DTI,在工作站上重建部分各向异性(FA)图、表观弥散系数(ADC)图和三维白质纤维束图,选择肿瘤核心实质区和对侧镜像区为兴趣区,测量FA和ADC值,并进行t检验.结果脑膜瘤、转移瘤和胶质瘤的FA值分别为0.36±0.08、0.28±0.03、0.18 ±0.06,FA值在脑膜瘤与转移瘤、脑膜瘤与胶质瘤、转移瘤与胶质瘤之间差异均有统计学意义(P＜0.05).脑膜瘤、转移瘤和胶质瘤的ADC值分别为1.72 ±0.10、1.52±0.22、1.34±0.14,ADC值在脑膜瘤与转移瘤、脑膜瘤与胶质瘤、转移瘤与胶质瘤之间差异均有统计学意义(P＜0.05).结论 DTI对脑膜瘤、转移瘤和胶质瘤的鉴别具有很高的临床价值.
목적 탐토뇌종류미산장량성상(DTI)적특점급기재뇌종류중적진단화감별진단개치.방법 대39례경병리증실적뇌종류환자(뇌막류10례,효질류17례,전이류12례),채용PhilipsAchieva 1.5 T자공진행상규MRI화DTI,재공작참상중건부분각향이성(FA)도、표관미산계수(ADC)도화삼유백질섬유속도,선택종류핵심실질구화대측경상구위흥취구,측량FA화ADC치,병진행t검험.결과 뇌막류、전이류화효질류적FA치분별위0.36±0.08、0.28±0.03、0.18 ±0.06,FA치재뇌막류여전이류、뇌막류여효질류、전이류여효질류지간차이균유통계학의의(P＜0.05).뇌막류、전이류화효질류적ADC치분별위1.72 ±0.10、1.52±0.22、1.34±0.14,ADC치재뇌막류여전이류、뇌막류여효질류、전이류여효질류지간차이균유통계학의의(P＜0.05).결론 DTI대뇌막류、전이류화효질류적감별구유흔고적림상개치.
Objective To study the characteristics of diffusion tensor imaging (DTI) in brain tumor and it's diagnosis and differential diagnosis value.Methods Thirty-nine patients with brain tumors proven by pathologically (10 meningioma,17 glioma,12 metastatic tumors) were enrolled,by using Philips Achieva 1.5 T MRI,conventional MRI and DTI were underwent on them,fractional anisotropy (FA) maps,apparent diffusion coefficient (ADC) maps and three dimensional white matter fiber bundle map were reconstructed in the workstation.The core substance of the tumor area and the contralateral mirror area were selected as the region of interest,and FA and ADC values of them were measured,and t test was performed.Results The FA values of meningioma,metastases tumors and gliomas were 0.36 ± 0.08,0.28 ± 0.03,0.18 ± 0.06,respectively,and the differences among them were significant( P ＜ 0.05).The ADC values of meningioma,metastases tumors and gliomas were 1.72 ± 0.10,1.52 ± 0.22,1.34 ± 0.14,respectively,and the differences among them were significant( P ＜ 0.05).Conclusion DTI has high clinical value in identification of meningiomas,metastatic tumors and glioma.