国际检验医学杂志
國際檢驗醫學雜誌
국제검험의학잡지
INTERNATIONAL JOURNAL OF LABORATORY MEDICINE
2009年
12期
1169-1170,1172
,共3页
王群兴%向贵州%左江成%叶湘
王群興%嚮貴州%左江成%葉湘
왕군흥%향귀주%좌강성%협상
NT-ProBNP%Q波%ST段升高型急性心梗%预后
NT-ProBNP%Q波%ST段升高型急性心梗%預後
NT-ProBNP%Q파%ST단승고형급성심경%예후
NT-ProBNP%Qwave%ST segment elevated myocardial infarction (STEMI)%Prognosis
目的 分析血浆N-端脑钠肽(NT-ProBNP)水平、Q波与ST段回落(STR)之间的相关性,评价血浆NT-ProBNP水平、Q波和STR在ST段升高型急性心肌梗死溶栓治疗后的疗效监测价值.方法 收集82例STEMI病例,根据溶栓治疗后STR百分比分为STR(-)组(<50%STR)和STR(+)gll(50%STR),测定血浆NT-ProBNP水平、血压、Q波、心率、LVEF、C反应蛋白(CRP)、血糖(GLU)、肌酐(Crea),计算肾小球滤过率(GRF).结果 2组间血浆NT-ProBNP、Q波、LVEF水平差异有统计学意义(P<0.01);Pearson's相关性分析发现,血浆NT-ProBNP水平与STR之间呈显著负相关,相关系数为-0.205,P<0.001;Logistic多元回归分析发现,Q波和血浆NT-ProBNP水平进入回归方程.结论 NT-ProBNP水平与STR密切相关.Q波和血浆NT-ProBNP水平是STR回落不良的独立危险因素.联合NT-ProBNP、Q波和STR能更全面准确评价和监测STEMI溶栓治疗效果.
目的 分析血漿N-耑腦鈉肽(NT-ProBNP)水平、Q波與ST段迴落(STR)之間的相關性,評價血漿NT-ProBNP水平、Q波和STR在ST段升高型急性心肌梗死溶栓治療後的療效鑑測價值.方法 收集82例STEMI病例,根據溶栓治療後STR百分比分為STR(-)組(<50%STR)和STR(+)gll(50%STR),測定血漿NT-ProBNP水平、血壓、Q波、心率、LVEF、C反應蛋白(CRP)、血糖(GLU)、肌酐(Crea),計算腎小毬濾過率(GRF).結果 2組間血漿NT-ProBNP、Q波、LVEF水平差異有統計學意義(P<0.01);Pearson's相關性分析髮現,血漿NT-ProBNP水平與STR之間呈顯著負相關,相關繫數為-0.205,P<0.001;Logistic多元迴歸分析髮現,Q波和血漿NT-ProBNP水平進入迴歸方程.結論 NT-ProBNP水平與STR密切相關.Q波和血漿NT-ProBNP水平是STR迴落不良的獨立危險因素.聯閤NT-ProBNP、Q波和STR能更全麵準確評價和鑑測STEMI溶栓治療效果.
목적 분석혈장N-단뇌납태(NT-ProBNP)수평、Q파여ST단회락(STR)지간적상관성,평개혈장NT-ProBNP수평、Q파화STR재ST단승고형급성심기경사용전치료후적료효감측개치.방법 수집82례STEMI병례,근거용전치료후STR백분비분위STR(-)조(<50%STR)화STR(+)gll(50%STR),측정혈장NT-ProBNP수평、혈압、Q파、심솔、LVEF、C반응단백(CRP)、혈당(GLU)、기항(Crea),계산신소구려과솔(GRF).결과 2조간혈장NT-ProBNP、Q파、LVEF수평차이유통계학의의(P<0.01);Pearson's상관성분석발현,혈장NT-ProBNP수평여STR지간정현저부상관,상관계수위-0.205,P<0.001;Logistic다원회귀분석발현,Q파화혈장NT-ProBNP수평진입회귀방정.결론 NT-ProBNP수평여STR밀절상관.Q파화혈장NT-ProBNP수평시STR회락불량적독립위험인소.연합NT-ProBNP、Q파화STR능경전면준학평개화감측STEMI용전치료효과.
Objective To investigate the association between plasma level of N-terminal pro-B-type natriuretic peptide (NT-ProBNP), Q wave and ST-segment resolution (STR), and evaluate the clinical value of NT-ProBNP, Q wave and STR in monitoring of therapeutic effect of thrombolysis in ST segment elevated myocardial infarction (STEMI). Methods According to STR percentage (STR%) after thrombolysis, 82 cases of STEMI were divided into STR ( -) group (<50% STR) and STR ( + ) 050% STR).Plasma NT-ProBNP level, blood pressure, Q wave, heart rate, left ventricular ejection fraction (LVEF), C reactive protein (CRP), blood glucose (GLU) and creatinine (Crea) were measured, and glomerular filtration rate (GRF) was calculated. Results There were statistical differences in plasma NT-ProBNP level, Q wave and LVEF between two groups (P<0. 01). Pearson's correlation analysis showed plasma NT-ProBNP was negatively correlative to STR (r = - 0. 205) (P<0. 001). Logstic multiple regression analysis showed that Q wave and plasma NT-ProB-NP level were enrolled in the regression equation. Conclusion Plasma NT-ProBNP level is closely associated with STR. Q wave and plasma NT-ProBNP level are risk factors for infaust STR. Combination of NT-ProBNP level, Q wave and STR may evaluate and monitor the therapeutic effect of thrombolysis in ST segment elevated myocardial infarction (STEMI) accurately and completely.
