生物化学与生物物理进展
生物化學與生物物理進展
생물화학여생물물리진전
PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS
2009年
11期
1394-1401
,共8页
发展性阅读障碍%脑结构%脑功能%脑功能连接
髮展性閱讀障礙%腦結構%腦功能%腦功能連接
발전성열독장애%뇌결구%뇌공능%뇌공능련접
developmental dyslexia%brain structure%brain function%brain functional connection
发展性阅读障碍是一种特殊的学习障碍,发展性阅读障碍的脑机制一直是研究者们关心的一个重要问题.随着脑成像技术的应用,人们在发展性阅读障碍的脑机制研究方面取得了重大进展.脑结构研究发现,发展性阅读障碍者在颞-顶叶、颢.枕叶、额下回、小脑等区域都存在一定的脑结构异常,这些脑结构异常要么表现在某个脑区的结构上,要么表现某个脑区结构的左右不对称性上.脑功能研究发现,发展性阅读障碍者出现脑结构异常的区域也大多表现出脑功能的异常.脑功能连接的研究发现,发展性阅读障碍者脑功能连接的异常不仅涉及到同侧脑区前后部分的连接,还涉及双侧脑区相应部分的连接.另外,中文发展性阅读障碍的研究发现了与拼音文字发展性阅读障碍不同的脑机制.这些研究成果为进一步揭示发展性阅读障碍的脑机制以及拓展中文发展性阅读障碍的研究提供了借鉴.
髮展性閱讀障礙是一種特殊的學習障礙,髮展性閱讀障礙的腦機製一直是研究者們關心的一箇重要問題.隨著腦成像技術的應用,人們在髮展性閱讀障礙的腦機製研究方麵取得瞭重大進展.腦結構研究髮現,髮展性閱讀障礙者在顳-頂葉、顥.枕葉、額下迴、小腦等區域都存在一定的腦結構異常,這些腦結構異常要麽錶現在某箇腦區的結構上,要麽錶現某箇腦區結構的左右不對稱性上.腦功能研究髮現,髮展性閱讀障礙者齣現腦結構異常的區域也大多錶現齣腦功能的異常.腦功能連接的研究髮現,髮展性閱讀障礙者腦功能連接的異常不僅涉及到同側腦區前後部分的連接,還涉及雙側腦區相應部分的連接.另外,中文髮展性閱讀障礙的研究髮現瞭與拼音文字髮展性閱讀障礙不同的腦機製.這些研究成果為進一步揭示髮展性閱讀障礙的腦機製以及拓展中文髮展性閱讀障礙的研究提供瞭藉鑒.
발전성열독장애시일충특수적학습장애,발전성열독장애적뇌궤제일직시연구자문관심적일개중요문제.수착뇌성상기술적응용,인문재발전성열독장애적뇌궤제연구방면취득료중대진전.뇌결구연구발현,발전성열독장애자재섭-정협、호.침협、액하회、소뇌등구역도존재일정적뇌결구이상,저사뇌결구이상요요표현재모개뇌구적결구상,요요표현모개뇌구결구적좌우불대칭성상.뇌공능연구발현,발전성열독장애자출현뇌결구이상적구역야대다표현출뇌공능적이상.뇌공능련접적연구발현,발전성열독장애자뇌공능련접적이상불부섭급도동측뇌구전후부분적련접,환섭급쌍측뇌구상응부분적련접.령외,중문발전성열독장애적연구발현료여병음문자발전성열독장애불동적뇌궤제.저사연구성과위진일보게시발전성열독장애적뇌궤제이급탁전중문발전성열독장애적연구제공료차감.
Developmental dyslexia is a specific learning disability. The cerebral mechanism of development dyslexia is an important topic that has fascinated many researchers. With the introduction of brain imaging in studies of cerebral mechanism of development dyslexia, many achievements have been made. Studies of developmental dyslexia structure image found that development dyslexia showed brain structure abnormal in the parietotemporal region, occipitotemporal cortex, inferior frontal gyrus, and cerebellum et al, manifesting either in one specific area or by the asymmetry of one area; the functional image studies revealed that development dyslexia showed activity abnormal in most regions that proved to display structure abnormality; studies of brain functional connectivity demonstrates that the abnormality of development dyslexia happened not only in the connection between front-back part in one cerebral hemisphere, but also in the connection between the two hemispheres. In addition, some studies indicate Chinese development dyslexia has different brain mechanisms compared to that of alphabetic languages. These findings provide valuable insight for future developmental cerebral mechanisms research and for the expansion of Chinese development dyslexia research.