中华老年医学杂志
中華老年醫學雜誌
중화노년의학잡지
Chinese Journal of Geriatrics
2012年
9期
797-799
,共3页
肾肿瘤%淋巴瘤%回顾性研究
腎腫瘤%淋巴瘤%迴顧性研究
신종류%림파류%회고성연구
Kidney neoplasms%Lymphoma%Retrospective studies
目的 探讨原发性肾淋巴瘤的临床特点和诊治方法. 方法 回顾性分析9例原发性肾淋巴瘤患者的临床数据. 结果 9例患者中,男5例,女4例,年龄47～75岁.单侧8例,双侧1例.单侧腰痛或肾区疼痛4例,体检发现3例,发热3例,体质量减轻2例,血尿1例,腹胀1例.血乳酸脱氢酶(LDH)292～2696 U/L升高7例；血β2微球蛋白(β2-MG)3.14～6.29 mg/L5例升高.B超检查显示肾区中低回声结构.CT检查显示一侧或双侧肾占位.病理诊断均为非霍奇金淋巴瘤,T细胞型1例,B细胞型8例.8例手术患者术后给予化疗(或联合靶向治疗)、放疗、免疫生物治疗.2例死亡,生存期分别为5个月和13个月.4例健在,随访期分别为1年、2年、3年、5年.2例外地患者失访.仅行活检的1例,给予化疗后死亡,总生存期11个月. 结论 原发性肾淋巴瘤临床表现缺乏特异性,术前诊断困难,治疗上主要采用手术联合放化疗.
目的 探討原髮性腎淋巴瘤的臨床特點和診治方法. 方法 迴顧性分析9例原髮性腎淋巴瘤患者的臨床數據. 結果 9例患者中,男5例,女4例,年齡47～75歲.單側8例,雙側1例.單側腰痛或腎區疼痛4例,體檢髮現3例,髮熱3例,體質量減輕2例,血尿1例,腹脹1例.血乳痠脫氫酶(LDH)292～2696 U/L升高7例；血β2微毬蛋白(β2-MG)3.14～6.29 mg/L5例升高.B超檢查顯示腎區中低迴聲結構.CT檢查顯示一側或雙側腎佔位.病理診斷均為非霍奇金淋巴瘤,T細胞型1例,B細胞型8例.8例手術患者術後給予化療(或聯閤靶嚮治療)、放療、免疫生物治療.2例死亡,生存期分彆為5箇月和13箇月.4例健在,隨訪期分彆為1年、2年、3年、5年.2例外地患者失訪.僅行活檢的1例,給予化療後死亡,總生存期11箇月. 結論 原髮性腎淋巴瘤臨床錶現缺乏特異性,術前診斷睏難,治療上主要採用手術聯閤放化療.
목적 탐토원발성신림파류적림상특점화진치방법. 방법 회고성분석9례원발성신림파류환자적림상수거. 결과 9례환자중,남5례,녀4례,년령47～75세.단측8례,쌍측1례.단측요통혹신구동통4례,체검발현3례,발열3례,체질량감경2례,혈뇨1례,복창1례.혈유산탈경매(LDH)292～2696 U/L승고7례；혈β2미구단백(β2-MG)3.14～6.29 mg/L5례승고.B초검사현시신구중저회성결구.CT검사현시일측혹쌍측신점위.병리진단균위비곽기금림파류,T세포형1례,B세포형8례.8례수술환자술후급여화료(혹연합파향치료)、방료、면역생물치료.2례사망,생존기분별위5개월화13개월.4례건재,수방기분별위1년、2년、3년、5년.2예외지환자실방.부행활검적1례,급여화료후사망,총생존기11개월. 결론 원발성신림파류림상표현결핍특이성,술전진단곤난,치료상주요채용수술연합방화료.
Objective To discuss the diagnosis and treatment of primary renal lymphoma.Methods The clinical data of 9 cases with primary renal lymphoma were retrospectively analyzed.Results Among 9 cases aged 47-75 years,5 cases were male,4 female.8 cases presented with unilateral and 1 case with bilateral masses.4 cases had lumbar pain,3 cases were founded by regular health examination,3 cases with fever and 2 cases with body weight loss,1 case had haematuria and 1 case with abdominal distension.7 cases had an elevated serum lactate dehydrogenase(292 -2696 U/L)and 5 cases had higher β2 microglobulin(3.14 -6.29 mg/L).The CT showed occupied lesions in renal.Under the type-B ultrasonic,a lump in the kidney was found.One case was diagnosed as T cell nonHodgkin's lymphoma,8 cases as B cell non- Hodgkin' s lymphoma by pathology.8 cases had kidney removed and received chemotherapy or plus target therapy,radiotherapy,immunotherapy.2 patients died with 5,13 months survival after operation.4 cases have been followed up for 1,2,3,5 years,respectively.2 cases were missed.1 case only under biopsy died 11 months after chemotherapy.Conclusions Because of no characteristic clinical appearance,the diagnosis of primary renal lymphoma could not be made preoperatively.The principal treatment consists of kidney resection and adjuvant combination chemotherapy.
