中华行为医学与脑科学杂志
中華行為醫學與腦科學雜誌
중화행위의학여뇌과학잡지
CHINESE JOURNAL OF BEHAVIORAL MEDICINE AND BRAIN SCIENCE
2009年
4期
328-330
,共3页
杨博%苗丹民%吕静%张焱%薛昀赟
楊博%苗丹民%呂靜%張焱%薛昀赟
양박%묘단민%려정%장염%설윤빈
事件相关电位%注意测验%脑力疲劳
事件相關電位%註意測驗%腦力疲勞
사건상관전위%주의측험%뇌력피로
Event-related potential(ERP)%Attention test%Mental fatigue
目的 建立脑力疲劳研究的实验室模型,探讨和评估持续认知操作任务前后注意测验和P300的变化.方法 20名青年男性受试做自身前后对照,持续完成8h的认知操作任务,在任务前后分别完成注意测验和事件相关电位(ERP)的测量,并对被试的主观疲劳感做出评价.结果 脑力疲劳前后注意测验成绩差异有显著性,黑红数字表法疲劳前后平均完成测验时间分别为(130.6±20.6)s和(142.4±24.6)s(P <0.05);注意分配检查法疲劳前后注意分配量的平均值分别为(0.86±0.06)和(0.79±0.05)(P <0.05).P300潜伏期前后比较差异无显著性,脑力疲劳后波幅明显减小,Fz点疲劳前后平均波幅分别为(7.8±5.1)μV和(5.4±5.6)μV(P <0.05).结论 事件相关电位P300的波幅差值能够为持续认知操作任务诱发脑力疲劳评估提供神经电生理证据.
目的 建立腦力疲勞研究的實驗室模型,探討和評估持續認知操作任務前後註意測驗和P300的變化.方法 20名青年男性受試做自身前後對照,持續完成8h的認知操作任務,在任務前後分彆完成註意測驗和事件相關電位(ERP)的測量,併對被試的主觀疲勞感做齣評價.結果 腦力疲勞前後註意測驗成績差異有顯著性,黑紅數字錶法疲勞前後平均完成測驗時間分彆為(130.6±20.6)s和(142.4±24.6)s(P <0.05);註意分配檢查法疲勞前後註意分配量的平均值分彆為(0.86±0.06)和(0.79±0.05)(P <0.05).P300潛伏期前後比較差異無顯著性,腦力疲勞後波幅明顯減小,Fz點疲勞前後平均波幅分彆為(7.8±5.1)μV和(5.4±5.6)μV(P <0.05).結論 事件相關電位P300的波幅差值能夠為持續認知操作任務誘髮腦力疲勞評估提供神經電生理證據.
목적 건립뇌력피로연구적실험실모형,탐토화평고지속인지조작임무전후주의측험화P300적변화.방법 20명청년남성수시주자신전후대조,지속완성8h적인지조작임무,재임무전후분별완성주의측험화사건상관전위(ERP)적측량,병대피시적주관피로감주출평개.결과 뇌력피로전후주의측험성적차이유현저성,흑홍수자표법피로전후평균완성측험시간분별위(130.6±20.6)s화(142.4±24.6)s(P <0.05);주의분배검사법피로전후주의분배량적평균치분별위(0.86±0.06)화(0.79±0.05)(P <0.05).P300잠복기전후비교차이무현저성,뇌력피로후파폭명현감소,Fz점피로전후평균파폭분별위(7.8±5.1)μV화(5.4±5.6)μV(P <0.05).결론 사건상관전위P300적파폭차치능구위지속인지조작임무유발뇌력피로평고제공신경전생리증거.
Objective To establish the laboratory research model of mental fatigue,as well as to discuss and assess the changes of attention test and P300 before and after mental fatigue. Methods 20 young male students continued to complete 8h cognitive performance tasks. Auditory P300 component (evoked by oddball paradigm), attention test and the self-rating scale for subjective fatigue symptoms were recorded before and after tasks.Results Before and after mental fatigue,there was significant difference of attention test.In black-red number table test,the average time used for test completion before and after mental fatigue were respectively (130.6±20.6)s and (142.4±24.6)s,P <0.05.In attention diversion check,the average attention assignment before and after mental fatigue were respectively 0.86±0.06 and 0.79±0.05(P <0.05).There was no significant difference of P300 latency change, but there was significant difference of P300 amplitude change. The average amplitudes on Fz before and after mental fatigue were respectively (7.8±5.1)μV and (5.4±5.6)μV(P <0.05).Conclusion The amplitude change of P300 provides neuro-electrophysiological evidence for diagnosing mental fatigue.