CAJ | 학술논문

目的研究绝经后妇女或子宫及双卵巢切除术后病人骨质疏松症应用雌激素预防的有效剂量。方法对120例患者给予不同剂量的药物治疗，测各剂量组血钙和血磷浓度及骨密度。结果雌激素0.625mg/d和1.25mg/d的剂量组血钙和血磷显著降低，更低剂量组病人骨质丢失明显(P＜0.01)。结论绝经后每日服用0.625mg雌激素可以预防骨质疏松症，更低剂量组则效果差，并要定期随访，安全性检查子宫及乳腺。
목적연구절경후부녀혹자궁급쌍란소절제술후병인골질소송증응용자격소예방적유효제량。방법대120례환자급여불동제량적약물치료，측각제량조혈개화혈린농도급골밀도。결과자격소0.625mg/d화1.25mg/d적제량조혈개화혈린현저강저，경저제량조병인골질주실명현(P＜0.01)。결론절경후매일복용0.625mg자격소가이예방골질소송증，경저제량조칙효과차，병요정기수방，안전성검사자궁급유선。
Objectives　 To research the effective does of estngen on preventing the postmen opausal osteoporosis or the isteioirisis women who received gysterectomy and ovariectomy.Methods　 120 patients were given different does of estrogen and had been visited for two years in orden to study the of Serum Calciun and phosphorus and the density of bone.Results　To the group of estrogen 0.625mg/day and 1.25mg/day,the of serum Calcium and phosphorus significantly decreased.The group of more lower dose of estrogen the losed bone was significant in(P＜0.01)。Conclusions　Estrogen 0.625mg day can Prevent Postmenopausal osteoporosis,the effect of more lower dosage is not as good as the precious one.at the same time the followmg visit and safety check are needed.