CAJ | 학술논문

冠心病仍然是全球的主要死亡原因.其所造成的心肌梗死及慢性心力衰竭对生活质量的影响和由此造成的高额医疗费用促使我们不断寻求新的医疗措施.近几年有关干细胞用于心肌梗死后心肌再生、心肌内新生血管形成,可能还会改善梗死后的心功能的研究成为心脏病学研究的最热门领域.尽管干细胞治疗有可能使心力衰竭的治疗得到彻底的革命,但仍有部分问题需要澄清.已发表的各个研究结果设计不尽相同,致使对该项治疗的效果较难得出一致的结论.但这些研究都强调干细胞治疗在未来心血管疾病的治疗中可能会发挥较大的作用.干细胞治疗与药学、外科及介入治疗的结合会显著改善冠心病患者的预后.
관심병잉연시전구적주요사망원인.기소조성적심기경사급만성심력쇠갈대생활질량적영향화유차조성적고액의료비용촉사아문불단심구신적의료조시.근궤년유관간세포용우심기경사후심기재생、심기내신생혈관형성,가능환회개선경사후적심공능적연구성위심장병학연구적최열문영역.진관간세포치료유가능사심력쇠갈적치료득도철저적혁명,단잉유부분문제수요징청.이발표적각개연구결과설계불진상동,치사대해항치료적효과교난득출일치적결론.단저사연구도강조간세포치료재미래심혈관질병적치료중가능회발휘교대적작용.간세포치료여약학、외과급개입치료적결합회현저개선관심병환자적예후.
Coronary artery disease remains the leading cause of death in the world. The high impact of its main sequelae (a-cute myocardial infarction and chronic heart failure} on the quality of life of patients and the cost of health care drives the search for new therapies. The recent finding that stem cells contribute to myocardial regeneration, neovascularization and possibly improve cardiac function after myocardial infarction makes stem cell therapy the most highly active research area in cardiology. Although the concept of stem cell therapy may revolutionize heart failure treatment, several obstacles need to be addressed. The published studies vary significantly in design, making it difficult to draw conclusions on the efficacy of this treatment. However, these studies highlight the landmark concept that stem celt therapy may play a major role in treating cardiovascular diseases in the near future. Stem cell therapy may be combined with pharmacological, surgical, and interventional therapy to improve outcome in patients with coronary artery disease.